Dr. Otis Brawley of Johns Hopkins shares his insight about cancer screening, focusing on prostate cancer. Dr. Brawley explains that while prostate cancer is common and serious, evidence supporting routine PSA screening is limited and inconsistent, leading major organizations to recommend shared decision-making between doctors and patients rather than universal screening. Men of Northwestern Sub-Saharan African ancestry have higher risk, but outcomes are equal across groups when high-quality care is provided, highlighting that disparities stem mainly from access to care, not biology. He emphasizes the importance of individualized screening decisions, treatment at strong medical centers, and patient engagement, and briefly describes Johns Hopkins’ MAPS peer-support program for cancer patients.