The Stem Cell Podcast

Ep. 147: “Targeted Repair in Blood Stem and Progenitor Cells” Featuring Dr. Jennifer Adair


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Guest:
Dr. Jennifer Adair is an Assistant Member in the Clinical Research Division at Fred Hutchinson Cancer Research Center. Her lab uses a combination of cell biology, molecular biology, chemistry, engineering, nanomedicine and bioinformatics to develop new gene therapy treatments for many different diseases, including cancer. Her goal is to develop safe, cost-effective and clinically relevant applications for gene therapy that can be implemented worldwide.
Featured Products and Resources:
Science in Seattle
StemSpan SFEM II
Resources and Links
Possible Drug Target for Heart Condition Identified - Researchers have found that a genetic mutation linked to dilated cardiomyopathy activates a signaling pathway that is normally turned off in healthy adult hearts.
Fibrosis Target Identified - Investigators have identified a protease that is activated by TGFβ that contributes to fibrosis development.
Improved Kidney Organoids - Scientists have developed a protocol for generating vascularized and functional human PSC-derived 3D kidney organoids, and used them to model disease.
New Tool for Immune Monitoring using Mass Cytometry - A mass cytometry workflow has been developed for identifying major immune cell lineages to improve biomarker discovery in immunotherapy trials.
Delayed Neurodevelopment in Zika-Exposed Children - In this prospective cohort study, the authors found that one third of children up to age three who were exposed to Zika in-utero had below-average neurological development.
Photo Reference: Courtesy of Dr. Jennifer Adair
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