Dr. Brenda Raud is a postdoctoral researcher at the Netherlands Cancer Institute. Her research focuses on T cell-based immunotherapies and immuno-oncology. Dr. Jason Goldsmith recently completed his postdoctoral fellowship at the University of Pennsylvania, and is now the Director of Donor Medical Sciences at Seres Therapeutics, a biotechnology company working to revolutionize treatment of a wide range of diseases by modulating the function of the human microbiome.

In addition to their work as researchers, Brenda and Jason are also hosts of the new Immunology Podcast, a sister podcast to the Stem Cell Podcast.

Single-Cell Synthetic Organism with Less Than 500 Genes – Researchers fabricated an artificial single-cell organism that can grow and divide like a normal cell, giving them insights into which genes are required for cell growth and division.

Humanized Skeletal Muscle Grown in Pigs – Scientists generated human-pig chimeric embryos with humanized skeletal muscle, as well as intraspecies chimeric pig embryos that were carried to term.

A 3D Model for Macular Degeneration – Researchers developed a 3D iPSC model of the retinal pigment epithelium-choriocapillaris complex, a complex that is damaged in age-related macular degeneration.

Human Brain Expansion Driven by an Early Cell Shape Transition   – Scientists grew human and ape cerebral organoids and discovered a transition state that is characterized by a change in cell shape, regulated by ZEB2, and delayed in humans.

Photo Reference: Courtesy of Drs. Brenda Raud and Jason Goldsmith

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