Dr. Melissa Little is the President, Keith Alm is the CEO, and Dr. Amander Clark is the Vice President of the International Society for Stem Cell Research (ISSCR). They discuss what they’re looking forward to at the upcoming ISSCR 2022 meeting, and the future of the organization and the stem cell research community.

An Alternate Tricarboxylic Acid Cycle – Researchers identified a non-canonical tricarboxylic acid cycle that is required for changes in cell state.

Replacing Microglia in Brain Disease – Scientists used circulation-derived myeloid cells to replace microglia in a mouse model of Prosaposin deficiency.

iPSC-Derived CAR T Cells – 3D organoid culture supported differentiation of CAR+ iPSCs into functional CAR T cells.

Cryopreservation of Islets for Transplantation – Researchers cryopreserved islets for nine months and implanted them into mice, leading to long-term glycemic control.

Photo Reference: Courtesy of ISSCR

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