Drs. Andrew Elefanty and Elizabeth Ng are Senior Principal Investigator and Principal Investigator, respectively, at the Murdoch Children’s Research Institute. In the Blood Development group, they aim to develop innovative cellular therapies for blood and  cartilage-related diseases. They talk about their recent study deriving and transplanting HSCs, their work on reporter lines, and their collaborative lab setup.

Heart Repair – An engineered epicardial engineered heart muscle allograft remuscularized a human heart. (2:04)

Causes of Preimplantation Failure – Single-embryo proteomics of poor-quality embryos provided insights into preimplantation development failure. (14:57)

Imprinting Abnormalities in Mammals – Researchers targeted imprinting abnormalities at their source — embryos from same-sex parents. (25:54)

Temperature-Controlled Cell Fate – Melt is a protein that reversibly clusters and translocates to the membrane in response to small temperature changes. (35:47)

Image courtesy of Drs. Andrew Elefanty and Elizabeth Ng

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