SGLT2 inhibitors and GLP1 agonists administered without metformin compared to other glucose‐lowering drugs in patients with type 2 diabetes mellitus to prevent cardiovascular events: A systematic review - Escobar - 2021 - Diabetic Medicine - Wiley Online Library
Yes these fancy new drugs work with and without metformin but that does not mean these drugs should be first line!!
Effect of a Single High Dose of Vitamin D3 on Hospital Length of Stay in Patients With Moderate to Severe COVID-19: A Randomized Clinical Trial | Complementary and Alternative Medicine | JAMA | JAMA Network
Yep even 200,000IU of vit D does nothing except raise your vit d level.
Diet and acne: review of the evidence from 2009 to 2020 - Dall’Oglio - - International Journal of Dermatology - Wiley Online Library
What you eat does mess with your acne, or at least says this large observational trial.
Statin treatment and muscle symptoms: series of randomised, placebo controlled n-of-1 trials | The BMJ
The muscle aches with statins is a common event that it occurs as frequently with the active drug as it does with placebo