Questioning Medicine

Episode 231: 231. Is Cancer Actually Associated with Weight Loss?


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>10% unintentional weight loss is most likely associated with 

  • gastrointestinal, liver, pancreatic, and biliary cancers (relative risks, 3.1–7.4);
  • Leukemia (RR, 4.2)
  • Breast, prostate, and gynecologic cancers were not associated with >10% weight loss


  • Wang Q-L et al. Cancer diagnoses after recent weight loss. JAMA 2024 Jan 23/30; 331:318. (https://doi.org/10.1001/jama.2023.25869)

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