Questioning Medicine

Episode 232: 232. Is the HPV vaccine that good?


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During 28 months of follow-up, absolute risks for progression from CIN2 to CIN3 (or worse) were as follows:

  • 23% among women vaccinated before age 15
  • 32% among women vaccinated between ages 15 and 20
  • 38% among women vaccinated after age 20
  • 38% among unvaccinated women


  • Krog L et al. Risk of progression of cervical intraepithelial neoplasia grade 2 in human papillomavirus–vaccinated and unvaccinated women: A population-based cohort study. Am J Obstet Gynecol 2023 Dec 30; [e-pub]. (https://doi.org/10.1016/j.ajog.2023.11.1235. opens in new tab)

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