This episode of the ICHE Podcast discusses the latest update to the Compendium, Strategies to prevent ventilator-associated pneumonia, ventilator-associated events, and nonventilator hospital-acquired pneumonia in acute-care hospitals: 2022 Update. ICHE Editor-in-Chief David P. Calfee, MD, MS interviews Michael Klompas, MD, Gregory P. Priebe, MD, and Eric C. Eichenwald, MD. The discuss updates to the document including changes to the essential and additional practices as well as implementation strategies. Strategies to prevent ventilator-associated pneumonia, ventilator-associated events, and nonventilator hospital-acquired pneumonia in acute-care hospitals: 2022 Update is available in the June issue of ICHE and can be found here: www.cambridge.org/iche.