Long-term care facilities face unique challenges in preventing healthcare-associated infections (HAIs) and managing multidrug-resistant organisms (MDROs). In this episode of The ICHE Podcast, Dr. Loren G. Miller (UCLA), Dr. Lyndsay M. O’Hara (University of Maryland School of Medicine), and Dr. Mary-Claire Roghmann (University of Maryland School of Medicine) share insights from their recent studies on decolonization and enhanced barrier precautions—two promising approaches for reducing infection risk among residents. They explore what the latest research tells us, where evidence gaps remain, and how facilities can apply practical, evidence-based interventions today to improve safety and quality of care.

UCI SHIELD Nursing Home Decolonization Toolkit: https://www.ucihealth.org/healthcare-professionals/shield/nursing-home-decolonization-toolkit

Enhanced barrier precautions to prevent transmission of *Staphylococcus aureus* and Carbapenem-resistant organisms in nursing home chronic ventilator units: https://www.cambridge.org/core/journals/infection-control-and-hospital-epidemiology/article/abs/enhanced-barrier-precautions-to-prevent-transmission-of-staphylococcus-aureus-and-carbapenemresistant-organisms-in-nursing-home-chronic-ventilator-units/43FBB459BB569B052DEDF87EA57193FB

Impact of routine chlorhexidine bathing and nasal iodophor on MDRO colonization and environmental contamination in nursing homes: https://www.cambridge.org/core/journals/infection-control-and-hospital-epidemiology/article/abs/impact-of-routine-chlorhexidine-bathing-and-nasal-iodophor-on-mdro-colonization-and-environmental-contamination-in-nursing-homes/EE2288CCE486EB4822A545BFE6210BA5