Go online to PeerView.com/HHW860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. Despite all of the advances in cancer treatment, there is still a significant need for a fourth pillar of therapy that can help improve outcomes for patients across a spectrum of solid tumors, such as glioblastoma, lung cancer, and GI malignancies. In this PeerView activity, an expert faculty panel will review the latest cutting-edge data supporting the use of tumor treating fields (TTFields) and synergistic combination strategies in established and emerging solid tumor indications from CNS to thoracic malignancies and beyond. You'll gain strategies to maximize treatment adherence and quality of life, develop skills for evidence-based adverse event management, and discover life-prolonging clinical trial opportunities. Delve into the science behind the use of TTFields in the treatment of solid malignancies, the latest evidence on the efficacy and safety of this modality across approved and emerging indications, and radiation oncology–focused guidance for the safe and effective incorporation of TTFields therapy in the clinic. Upon completion of this activity, participants should be better able to: Describe the mechanistic rationale and evidence supporting the use of TTFields for the treatment of patients with CNS, thoracic, and other aggressive solid tumors; Integrate TTFields into multimodal management protocols for appropriately selected patients with CNS, thoracic, and other solid malignancies; and Devise team-based strategies designed to mitigate and manage adverse events associated with TTFields to improve outcomes in patients with difficult-to-treat cancers.