Shares on Wednesday closed lower amid weak global cues as well as expiry of derivative contracts for March series. While the Nifty managed to hold 10,100-mark, the Sensex managed to close below 33,000.

The 30-share index, Sensex, has closed 200 points down at 32,968, while the Nifty ended at 10,113.7, down 70.50 points.

In the broader markets, Nifty Midcap index managed to underperform the benchmark indices. The index fell over 1 percent.

On a sectoral basis, all of them managed to close in the red, with financials and energy contributing 50 percent to the Nifty’s fall.

Among standalone stocks, Reliance Industries and ICICI Bank were the top losers. Meanwhile, in case of Nifty Bank, only Yes Bank and IndusInd managed to close in the green.

For the March series, both Sensex and Nifty have managed to shed a little over 2 percent, while the Bank Nifty and Nifty Midcap have fallen up to 3 percent.

Stocks in the news

Alkem Laboratories plunged 6 percent after the US health regulator issued 13 observations to its Daman facility and 1 to US plant.

Meanwhile, GlaxoSmithKline Consumer Healthcare fell 8 percent as its parent company is set to carry out a strategic review of Horlicks.

In the aviation space, Jet Airways fell around 4 percent as investors reacted to the buzz of salary delays in the firm.

In the healthcare segment, Fortis Healthcare slipped 13 percent as company board approved the demerger of its hospitals business to Manipal Hospital Enterprises.

Indoco Remedies dropped 13 percent after the UK healthcare regulator issued seven observations to company's Goa plant I.

Share of Biocon lost over 1 percent after gaining over 2 percent after it received marketing authorization approval from the European Commission.

Lastly, Persistent Systems’ share price dropped more than 11 percent after the company lowered its revenue and margin growth for last quarter of financial year 2017-18.