A security guard disappeared from his post without a trace; his remains were found a year later in a remote camp site. More than a decade would pass before a phone call breathed life into the cold case, a paint smear on the bottom of the victim's boot helped scientists determine what happened during the last hour of his life.

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For years, a woman suffered from what appeared to be the unpleasant side effects of lithium, a drug prescribed to treat bipolar disorder. When she died, investigators had to determine if her death was due to natural causes, suicide or murder.

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Time of death becomes pivotal after a pregnant woman is found murdered in her air-conditioned bedroom. A similarity between her death and an HBO movie gives forensic examiners the clues they need to thaw out the alibi of a cold-blooded killer.

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In 1984, hundreds of people in The Dalles, Oregon became ill with food poisoning. Local, state, and federal disease detectives slowly unraveled the medical mystery. Along with a unique strain of bacteria, they discovered a religious cult's bizarre plot to overthrow the government...using germ warfare.

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The man suffered a slow, agonizing death over a period of days. His wife maintained he killed himself, but police were skeptical... especially when they learned her first husband died when he was only 38-years old, and she refused to consent to an autopsy.

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When a dedicated, well-respected teacher disappeared, police had to determine if she'd gone on vacation without telling anyone or if she was the victim of foul play. Investigators turned to forensic science, hoping to find the answers they needed.

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A behavioral profile is helpful in a murder investigation, but it's not a road map to the killer. One such profile caused the Baton Rouge Police Department to search for the wrong man. They might have made an arrest had it not been for a DNA picture of the suspect painted by a molecular biologist.

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An Arizona surgeon is found stabbed to death. All signs point to a random attack until investigators uncover an unlikely suspect. Police work to unravel the mystery in a case of jealousy, rage, and the almighty dollar.

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The medical examiner ruled the death an accident, but the detectives investigating the case thought the evidence at the scene indicated otherwise. It would take three years, an exhumation, and a second autopsy to determine who was right.

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The autopsy on the badly burned body of Charles "Jack" Lynch led investigators to search for a couple of killers.

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