This week: Cryptogenic Stroke and Atrial Fibrillation, Naloxegol for Opioid-Induced Constipation Fahad and Amol want you to: 1. Appreciate the importance of subclinical atrial fibrillation in cryptogenic stroke and consider longer monitoring to detect it. 2. Recognize Naloxegol as a targeted therapy for opioid-induced constipation that is more effective than placebo but its effectiveness has not been compared directly with existing laxative therapies. ...

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