Episode Summary:Plants have supported life on this planet since the daw of time. This episode elaborates on the following:History of plants in human healthWhat are the medicinal component of plants?Plants and their use in both ancient/modern medicine The necessity of continued plant explorationEpisode References:Medicinal Plant reference in the Holy Quran: https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0032-1307617Ebers Papyrus: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3358962/?report=printable#ref5Percentage of plant-derived compounds as pharmaceutical drugs: https://pubs.acs.org/doi/10.1021/acs.jnatprod.5b01055Top countries for plant biodiversity: https://ac.els-cdn.com/S2468265916300300/1-s2.0-S2468265916300300-main.pdf?_tid=5acb5eaf-b584-4c8c-9756-ae1bd0398b8a&acdnat=1541541826_493b8733e36afce8e2b252281a0c8eb3

Episode Summary:You’ve likely seen news articles floating around about startup companies making meat without the cow, chicken, pig, or fish. This episode tackles the following:What is cultured meat?How is cultured meat made?What are the downsides of traditional meat?Potential benefits of cultured meatChallenges of cultured meatEpisode References:First example of meat made in a laboratory: https://www.sciencedirect.com/science/article/pii/S0309174012001210?via%3DihubInfectious diseases from livestock: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2865087/pdf/rstb20090133.pdf H1N1 Pandemic: http://www.who.int/csr/disease/swineflu/updates/en/ Food borne illnesses from meat: https://www.niddk.nih.gov/health-information/digestive-diseases/foodborne-illnesses

This episode will discuss the following:Explain the Good Food = Medicine conceptThe 4 basic components of foodMacronutrients 101Not all calories are of equal valueEpisode References:As an example to the Good Food = Medicine concept, see here for plants used during pregnancy, childbirth, and postpartum care in Laos: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2749814/pdf/1746-4269-5-25.pdf See here for a review on different protein types: https://www.jssm.org/vol3/n3/2/v3n3-2pdf.pdf Benefits of short chain fatty acids on human health: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756104/Correlation between fiber intake and decreased risk of disease: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3513325/pdf/nihms414391.pdf

You’ve likely heard something about cannabidiol (CBD) recently. This episode discusses the following:What is CBD?Where does CBD come from?Is CBD the same as marijuana?Is CBD legal?What are the potential health benefits of CBD?How does CBD work in the body?What to look for in a CBD-containing product?Episode References:CBD on Google Trends: https://trends.google.com/trends/explore?date=today%205-y&geo=US&q=cbdSee here for more reading on the different compounds in Cannabis sativa: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3736954/pdf/10.1177_2045125312457586.pdf FDA statement on the legality of CBD: https://www.fda.gov/NewsEvents/PublicHealthFocus/ucm421168.htm#dietary_supplements See here for Epidiolex published study: https://www.thelancet.com/action/showPdf?pii=S1474-4422%2815%2900379-8 Sam Vogelstein’s story regarding taking Epidiolex: https://www.npr.org/sections/health-shots/2018/08/06/632469743/how-one-familys-fight-with-epilepsy-led-to-the-first-marijuana-based-pharmaceutiDEA official statement on the rescheduling of Epidiolex—but not CBD: https://www.federalregister.gov/documents/2018/09/28/2018-21121/schedules-of-controlled-substances-placement-in-schedule-v-of-certain-fda-approved-drugs-containing Warning letters issued by the FDA related to CBD: https://www.fda.gov/newsevents/publichealthfocus/ucm484109.htm Discovery of molecules in the body that bind to cannabinoid receptors: http://science.sciencemag.org/content/258/5090/1946.long

Discussed in this episode are the following issues related to the health crisis sweeping the earth like a noxious plague:What does it mean to be healthy?The epic breakdown of human healthThe name given for this breakdown of healthDefinition of metabolic syndrome3 Maxims for optimum healthEpisode References:Definition health from a systems biology standpoint: https://www.cell.com/cell-metabolism/fulltext/S1550-4131(17)30092-XLeading causes of death in the US: https://www.cdc.gov/nchs/fastats/leading-causes-of-death.htmObesity rates in the US: https://www.cdc.gov/obesity/data/adult.htmlPrevalence of diabetes in the US: http://www.diabetes.org/diabetes-basics/statistics/Heart diseases statistics in the US: https://www.cdc.gov/heartdisease/facts.htmCriteria for Metabolic Syndrome: https://www.ahajournals.org/doi/abs/10.1161/CIRCULATIONAHA.109.192644?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub%3DpubmedSelected metabolic syndrome rates worldwide: https://bmcpublichealth.biomedcentral.com/articles/10.1186/s12889-017-4041-1  Sleep cleans the brain: http://science.sciencemag.org/content/342/6156/373Effect of stress on human health: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3380124/pdf/dmj-36-207.pdf

This introductory episode discusses the following:The body as an assetThe health/knowledge gapHow to assess the credible from the fluff?Finding your Health Numbers (H#s)Episode References:Peer-reviewed journal impact factors: https://tools.niehs.nih.gov/srp/publications/highimpactjournals.cfm  Velocity numbers/speeds for airplanes: https://www.grc.nasa.gov/www/k-12/Summer_Training/Elementary97/planearticle.html