While much is still unknown about COVID-19, the medical community has made significant strides throughout 2020 in its understanding of this disease, as well as how health-care systems can adapt to better care for patients. In the first installment of this three-part series, hear from clinicians who have spent months on the COVID-19 front lines about changes to systems/ICU organization, visitation and family-centered care, and medical education. (Originally recorded December 3, 2020) Moderator: Christopher L. Carroll, MD, FCCP. Panelists: Mangala Narasimhan, DO, FCCP; Geneva B. Tatem, MD, FCCP; and Sara Hegab, MD. For more tools to help in the fight against COVID-19, visit CHEST’s COVID-19 Resource Center at chestnet.org/COVID19.