In the second installment of this three-part series on what the medical community has learned about COVID-19 over the past year, hear about the evolution of critical care management, respiratory support strategies, COVID-19-targeted therapies, and treatment of venous thromboembolism. (Originally recorded December 10, 2020) Moderator: Kevin K. Chung, MD. Panelists: Richard A. Oeckler, MD, PhD, FCCP; Nida Qadir, MD; Tamas Szakmany, MD, PhD; and Victor Test, MD, FCCP. For more tools to help in the fight against COVID-19, visit CHEST’s COVID-19 Resource Center at chestnet.org/COVID19.