Hormone imbalance, weight gain, brain fog, and burnout after 40? You’re not alone. In this episode of Doing Life Different, Lesa Koski welcomes functional medicine practitioner Marrie Simpson for an open, empowering conversation about hormones, metabolic health, and how women can take back control of their well-being—naturally and holistically.

Marrie shares her personal journey from prescription-based medicine to root-cause healing, and dives into actionable steps women can take to balance hormones, increase energy, improve sleep, and support metabolic fitness—especially during perimenopause and menopause.

If you're feeling stuck, overwhelmed, or out of balance, this episode is packed with hope, education, and next steps—without the overwhelm. Whether you're dealing with hot flashes, insomnia, low libido, or just a nagging feeling of "not quite right," you're in the right place.

🎧 Plus: Lesa shares her own experience navigating estrogen blockers after breast cancer—and how Marie's guidance has helped her reclaim her energy and mindset.

⏱️ Timestamps:

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• (00:00) Introduction: Meet Marrie Simpson
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• (03:15) Marrie’s journey from traditional medicine to functional healing
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• (09:42) How hormone imbalance affects women 40+
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• (15:27) Understanding perimenopause and estrogen dominance
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• (19:44) The real impact of cortisol, stress, and sleep
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• (23:16) Weight gain and metabolic slow-down in midlife
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• (30:03) What women can do naturally to support hormone health
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• (34:55) When hormone replacement therapy makes sense—and when it doesn’t
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• (42:48) Alcohol, estrogen, and breast cancer risk
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• (48:19) Why listening to your body is the most powerful strategy
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• (51:30) Final words of hope from Marie and Lesa
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✅ Key Takeaways:

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• 88% of chronic illnesses are connected to metabolic dysfunction—not genetics.
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• Cortisol and estrogen dominance are often the hidden culprits behind midlife weight gain and insomnia.
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• Women can take a natural approach to healing through diet, stress management, muscle preservation, and detoxification.
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• Hormone replacement therapy can be powerful—but only when individualized and timed correctly.
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• Alcohol increases breast cancer risk and interferes with hormone balance. (One glass of wine per night may not be as harmless as you think.)
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👩‍⚕️ Guest Bio: Marie Simpson, PA-C, IFMCP

Marrie Simpson is a licensed Physician Assistant and certified Functional Medicine Practitioner. Founder of Elevate Health and Wellness, Marrie blends her clinical training with deep compassion, science-backed protocols, and personalized coaching. With specialties in metabolic health, hormone balance, autoimmune conditions, and genetic optimization, Marie empowers women to heal root causes—not just symptoms.

🔗 Resource Links:

DIY Parenting Plan Course

Find More From Lesa Here!

Marrie Simpson’s Metabolic Reset

jjflizanes.com/lesa

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🔎 Tags/Keywords:

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