The COVID-19 coronavirus has upended American’s lives and heightened our anxieties. That’s likely to have a lot of political consequences. How do Americans respond to imminent threats and how does our anxiety change how we seek information, who we trust, and what policies we support? Bethany Albertson and Shana Gadarian find that Americans seek information, trust the experts, and seek protective policies in response to public health threats like infectious disease. But our biases increase and our instincts are often to blame outsiders. We explore research on anxiety in response to threats on a special conversational edition of the Science of Politics.