We all know the vow: “In sickness and in health.” But in reality, when serious illness enters a relationship, everything changes. A powerful mix of conflicting emotions can tug on people — love, devotion, grief, guilt, and even resentment. Illness can be a test — a trial by fire — but also an opportunity for growth.

On this episode, we hear from couples and families whose lives have been touched by illness and find out how they made it through. How were their relationships transformed? How did they not only survive — but thrive? And what helps people cope, and even appreciate the good moments? We hear stories about how cancer changed the trajectory of writer Delia Ephron’s life, the hidden struggles of family caregivers, and how one mother’s illness transformed her family’s life.

Also heard on this week’s episode: