Inside Exercise

Dr Glenn McConell chats with Professor Shona Halson from the Australian Catholic University, Melbourne, Australia. We chatted about how much sleep athletes need compared with how much sleep they actually get. Night sleep vs naps vs total sleep in athletes vs non athletes. The importance of consistency of sleep. Caffeine, sleep and exercise performance. Is overtraining actually a lot less common than believed? Ice baths may reduce hypertrophy with resistance training but improve team sports/endurance. Effects of compression garments on recovery. The effects of mental fatigue on exercise performance. A very interesting chat. Twitter: @ShonaHalson
0:00. Introduction + how Shona got into sports/exercise research
3:45. Defining what we mean by recovery and fatigue
5:40. How much sleep do athletes need/get?
11:30. If athletes extend their sleep they do better
13:05. Athletes night sleep vs total sleep per day (naps)
15:10. Physical load vs mental load and sleep
16:45. Sleep quality/architecture
20:15. Is one night of reduced sleep a problem?
21:15. Lack of sleep and perception of effort
22:20. Importance of sleep consistency/regularity
28:55. Does a lack of sleep reduce performance
29:56. Best to prioritize sleep or exercise?
34:27. Caffeine and sleep studies (hard to control)
39:15. Caffeine: responders and non responders etc
41:30. Genetics and sleep/can one sleep too much?
43:12. Intensified training vs overreaching vs overtraining
52:52. Ice baths/contrast baths, adaptations and recovery
1:03:00. Water, hydrostatic pressure and blood flow
1:05:25. Inflammation, anti-inflammatories and ice
1:07:30. Physical fatigue vs mental fatigue
1:11:00. Mental fatigue and exercise performance
1:13:40. Are wearables useful for gauging recovery?
1:16:24. Listening to your body
1:17:50. Compression garments and recovery
1:21:05. Menstrual cycling and sleep
1:22:30. Takeaway messages
1:23:30. Placebo effects
1:24:49. Outro (9 seconds)

Dr Glenn McConell chats with Assoc Prof Andre La Gerche a world leading Sports Cardiologist from St Vincent’s Institute of Medical Research, Melbourne, Australia. Acute exercise for long periods at a high intensity can result in abnormal right ventricle function. In addition, years of long, hard exercise training is associated with increased coronary artery calcium (CAC) levels and atrial fibrillation (AF). Despite this, Andre is a huge advocate of exercise across the population and generally even in these individuals. The evidence is that exercise training increase healthspan and reduces mortality rates despite some of these changes. A very important, interesting chat. Twitter: @ALaGerche
0:00. Introduction + how Andre got into sports/exercise research
5:30. Andre’s excellent marathon running
7:32. Is exercise good for the heart?
10:50. Media fear around ex and the heart
13:45. Increased CAC and heart attack risk
17:00. Exercise protective even if increased CAC
18:56. Andre hasn’t had a CAC scan
22:28. Plague build up in the coronary arteries
23:50. Some people never have coronary issues
24:50. Genetics and the heart
26:55. Jim Fixx: died running
27:40. How can exercise increase CAC?
32:00. Get into exercise slowly
33:30. Coronary “hot plagues” and heart attacks
35:30. Exercise before a heart operation
36:45. Exercise training increases hearts reserve with age
37:33. 1969 marathon WR holder Derek Clayton: still amazing heart
43:15. AF more common in endurance athletes
45:43. Female endurance athletes have increased AF
47:55. Generally if in doubt, keep exercising
50:43. Women have relatively more stable hearts
52:50. Cardiac screening of athletes
55:55. Ventricular arrhythmias: continue sport or not?
59:50. It's hard to estimate heart attack risk
1:01:58. Right ventricle after long hard races
1:08:10. Rare ventricular tachycardia in professional athletes
1:11:34. The importance of seeing a sports cardiologist
1:14:40. Big vs enormous hearts in top endurance athletes
1:18:10. Genetics and the heart
1:19:25. EPO, anabolic steroids, very hard training and the heart
1:24:20. Resistance training, anabolic steroids and the heart
1:28:15. Best exercise to do for the heart and health
1:29:50. What’s the cutoff of ex for increased AF?
1:33:50. Blood indicators of heart damage/recovery
1:36:45. Right ventricle “fatigue” and recovery
1:40:50. Heart failure/heart reserve and exercise (sex differences)
1:44:00. Don't assume sudden death in athletes drug related
1:45:45. Negative cardiac effects of the Covid19 vaccine in some people
1:50:12. Takeaway messages
1:52:38. Outro (9 seconds)
Inside Exercise brings to you the who's who of research in exercise metabolism, exercise physiology and exercise’s effects on health. With scientific rigor, these researchers discuss popular exercise topics while providing practical strategies for all.
The interviewer, Emeritus Professor Glenn McConell, has an international research profile following 30 years of Exercise Metabolism research experience while at The University of Melbourne, Ball State University, Monash University, the University of Copenhagen and Victoria University.
He has published over 120 peer reviewed journal articles and recently edited an Exercise Metabolism eBook written by world experts on 17 different topics (https://link.springer.com/book/10.1007/978-3-030-94305-9).
Connect with Inside Exercise and Glenn McConell at:
Twitter: @Inside_exercise and @GlennMcConell1
Instagram: insideexercise
Facebook: Glenn McConell
LinkedIn: Glenn McConell https://www.linkedin.com/in/glenn-mcconell-83475460
ResearchGate: Glenn McConell
Email: [email protected]
Subscribe to Inside exercise:
Spotify: shorturl.at/tyGHL
Apple Podcasts: shorturl.at/oFQRU
YouTube: https://www.youtube.com/@insideexercise
Anchor: https://anchor.fm/insideexercise
Google Podcasts: shorturl.at/bfhHI
Anchor: https://anchor.fm/insideexercise
Podcast Addict: https://podcastaddict.com/podcast/4025218
Not medical advice

Dr Glenn McConell chats with Professor Wim Derave from the Ghent University in Belgium. We talked about the different muscle fibres/fiber types in humans and his recent evidence that pure Type 2X muscle fibers may not really exist or maybe only in some sedentary individuals. He also made the point that muscle fiber type info is not used enough in sports contexts. He outlined some non invasive ways of estimating your muscle fibre types. Finally we discussed remarkable and important findings that antihistamines may reduce some exercise training adaptations. A very interesting, long chat. Twitter: @TeamDerave.
0:00. Introduction and how Wim got into exercise research
7:02. Different types of muscle fiber types
10:10. Humans tend to be a slow fiber type species
12:10. Humans hunt by wearing down our prey
17:50. Can ex training change muscle fiber type?
22:00. For sprinters the more fast fibers the better?
24:00. The different types of muscle fibers
26:58. He finds no type 2X muscle fibers in humans
31:00. Some sedentary people may have a few type 2X fibers
34:50. New methods to determine muscle fibre type
37:20. Coexistence of more than one fiber type within a fiber?
42:50. Slow twitch fibers are more efficient
43:44. Sedentary/tapering and type 2X fibers
46:30. More fast twitch fibers in insulin resistance
50:51. Non invasive ways to estimate muscle fibre type
57:20. Swimming vs muscle fiber type
1:00:02. 30 second cycling sprint to estimate muscle fiber type
1:05:10. Coaches and muscle fiber type
1:07:10. Applying muscle fiber type info to sport
1:09:20. Hamstring strains, overtraining, tapering and muscle fiber type
1:17:45. Slow fibers barely fatigue
1:19:30. Diet and muscle fiber type
1:30:30. Non muscle cells needed for skeletal muscle training adaptations
1:38:50. Antihistamines may reduce ex training adaptations
1:46:20. Sex differences and muscle fibre type
1:47:33. Age and muscle fibre type
1:49:35. Takeaway messages
2:00:51. Outro (9 seconds)
Inside Exercise brings to you the who's who of research in exercise metabolism, exercise physiology and exercise’s effects on health. With scientific rigor, these researchers discuss popular exercise topics while providing practical strategies for all.
The interviewer, Emeritus Professor Glenn McConell, has an international research profile following 30 years of Exercise Metabolism research experience while at The University of Melbourne, Ball State University, Monash University, the University of Copenhagen and Victoria University.
He has published over 120 peer reviewed journal articles and recently edited an Exercise Metabolism eBook written by world experts on 17 different topics (https://link.springer.com/book/10.1007/978-3-030-94305-9).
Connect with Inside Exercise and Glenn McConell at:
Twitter: @Inside_exercise and @GlennMcConell1
Instagram: insideexercise
Facebook: Glenn McConell
LinkedIn: Glenn McConell https://www.linkedin.com/in/glenn-mcconell-83475460
ResearchGate: Glenn McConell
Email: [email protected]
Subscribe to Inside exercise:
Spotify: shorturl.at/tyGHL
Apple Podcasts: shorturl.at/oFQRU
YouTube: https://www.youtube.com/@insideexercise
Anchor: https://anchor.fm/insideexercise
Google Podcasts: shorturl.at/bfhHI
Anchor: https://anchor.fm/insideexercise
Podcast Addict: https://podcastaddict.com/podcast/4025218
Not medical advice

Dr Glenn McConell chats with Professor José Calbet from the University of Las Palmas de Gran, Canary Islands, Spain. José has a very strong research record and is a global leader in his field. He has done amazing invasive exercise studies in humans to determine the limiting factor(s) to VO2 max. We talked about what is VO2 max, the factors determining VO2 max, the limits to VO2 max, the effects of VO2 max on exercise performance, pseudoanemia, VO2 max in females, VO2 max in masters athletes etc. In general he is finding the oxygen delivery is the main limiting factor to VO2 max. A very interesting, long chat. Twitter: @GRHEFS_ULPGC

Dr Glenn McConell chats with Professor Ylva Hellsten from the University of Copenhagen in Denmark. She is an authority on the effect of exercise on blood flow and cardiovascular function. We talked about heart rate before exercise and blood flow and blood pressure during and after exercise. She pointed out that muscle blood flow can increase by 100-fold during exercise! We discussed the effect of physical activity and aging/inactivity and menopause on the cardiovascular system. Also the protective effects of exercise training and the importance of doing the physical activity that you enjoy. A very interesting chat. Twitter: @CVgroupNEXS.

0:00. Introduction and how Ylva got into exercise research
5:15. Eccentric exercise induced muscle damage
6:45. Increases in heart rate before exercise
7:35. Increases in blood flow during exercise
11:15. Even passive movement of limbs can increase blood flow
13:15. How does exercise increase blood flow?
16:40. How much does muscle blood flow increase during exercise?
18:35. Achieving adequate blood pressure and blood flow during exercise
23:22. Are muscle capillaries all open even at rest?
29:18. What happens to blood flow after exercise?
31:00. Redundancy in regulation of blood flow during exercise
36:01. Closing off blood flow to some areas during exercise
38:24. Reduced blood pressure after exercise
42:12. Blood flow and blood pressure during resistance exercise
44:00. Blood flow restriction during contractions
46:28. Fainting with prolonged standing, especially in the heat
49:45. Exercise training reduces blood pressure
52:30. Aging/inactivity and the cardiovascular system
53:35. Optimal exercise to improve the cardiovascular system
1:02:15. Blood vessel function declines with age are partly inactivity
1:05:30. Menopause, exercise training and blood vessel function
1:13:27. Long term activity and blood vessel function
1:16:02. Effects of different types of exercise training
1:17:50. Large muscle mass exercise
1:19:30. Interval training/Do the physical activity that you enjoy
1:20:55. Different ways to measure blood flow
1:22:59. Blood flow during exercise in disease groups
1:27:02. Isolated blood vessel cells from exercised muscle
1:31:42. Ylva’s research: does she usually find what she expects?
1:35:12. Takeaway messages
1:38:21. Outro (9 seconds)
Inside Exercise brings to you the who's who of research in exercise metabolism, exercise physiology and exercise’s effects on health. With scientific rigor, these researchers discuss popular exercise topics while providing practical strategies for all.
The interviewer, Emeritus Professor Glenn McConell, has an international research profile following 30 years of Exercise Metabolism research experience while at The University of Melbourne, Ball State University, Monash University, the University of Copenhagen and Victoria University.
He has published over 120 peer reviewed journal articles and recently edited an Exercise Metabolism eBook written by world experts on 17 different topics (https://link.springer.com/book/10.1007/978-3-030-94305-9).
Connect with Inside Exercise and Glenn McConell at:
Twitter: @Inside_exercise and @GlennMcConell1
Instagram: insideexercise
Facebook: Glenn McConell
LinkedIn: Glenn McConell https://www.linkedin.com/in/glenn-mcconell-83475460
ResearchGate: Glenn McConell
Email: [email protected]
Subscribe to Inside exercise:
Spotify: shorturl.at/tyGHL
Apple Podcasts: shorturl.at/oFQRU
YouTube: https://www.youtube.com/@insideexercise
Anchor: https://anchor.fm/insideexercise
Google Podcasts: shorturl.at/bfhHI
Anchor: https://anchor.fm/insideexercise
Podcast Addict: https://podcastaddict.com/podcast/4025218
Not medical advice

Dr Glenn McConell chats with his great collaborator Professor Erik Richter from the University of Copenhagen in Denmark. Erik is an absolute authority and the godfather of the field of glucose metabolism during exercise and how exercise increases insulin sensitivity in muscle. He was the first to show that contraction can increase muscle glucose uptake without insulin but at the same time exercise increases insulin sensitivity. Very relevant for all including people with diabetes. We talked about how exercise increases glucose uptake during exercise and how it increases insulin sensitivity after exercise. Limitations of determining insulin sensitivity using the “gold standard” euglycemic hyperinsulinemic clamp vs meals. We also talked a little about how exercise can reduce appetite (GLP1 and lactate) . A very interesting, fun chat. Twitter: @proferikrichter.

0:00. Introduction and how Erik got into exercise research after medicine
3:05. Henrik Galbo, Jen Holst GLP1, glycogen, exercise
5:32. Adrenaline, glycogen breakdown and glucose uptake
7:20. Niel Ruderman: exercise and insulin sensitivity
9:32. Contraction increases glucose uptake independent of insulin
11:30. Relevance to type 1 diabetes
14:20. High intensity exercise increases blood glucose levels
16:15. Normal increases in insulin sensitivity after exercise in T2D
17:15. Regulation of glucose uptake into muscle during exercise
20:15. Appears AMPK not needed for glucose uptake during exercise
23:10. Reactive oxygen species and glucose uptake during exercise
24:05. Complexity of the many changes in muscle during exercise
27:00. Is there still a place for integrative physiology?
28:30. The incredible methods that Erik uses in human exercise studies
31:40. Limitations of using clamps for insulin sensitivity after exercise
35:35. Meals result in higher glucose uptake after ex than clamps
41:50. Is glucose uptake into non exercise muscle inhibited?
42:58. What need to consider when doing a clamp
45:10. Are continuous glucose monitors worth using?
47:32. Incretins (including GLP1) and insulin sensitivity after exercise
49:57. Effects of one bout vs chronic exercise (training) on insulin sensitivity
52:56. Does muscle glycogen stimulate insulin sensitivity?
57:51. Endurance vs resistance exercise for insulin sensitivity?
59:14. Erik’s impressive recent running times
59:54. HIIT, hyperglycemia, lactate, GDF15 and appetite
1:04:10. RED-S, fasting and insulin sensitivity
1:10:38. Gut glucose transport into the blood
1:15:16. A lot of glucose passes through the liver after exercise
1:16:20. How does glucose leave the capillaries to enter the muscle?
1:22:12. Takeaway messages
1:23:52. Outro (9 seconds)

Dr Glenn McConell chats with Associate Professor Jeremy Loenneke from the University of Mississippi, USA. He is an expert on resistance training and in particular the effect of blood flow restriction (BFR) on muscle hypertrophy and strength. He is finding that you can get similar increases in hypertrophy, and close to similar increases in strength, by conducting low load resistance training with blood flow restriction compared with high load resistance training. Surprisingly, he is also finding that there can be dissociations between increases in strength and increases in hypertrophy when undertake resistance training. We also discussed other interesting research he has been undertaking. I was actually blown away by some of his findings. A very interesting, long chat. Twitter: @jploenneke
0:00. Introduction and how Jeremy got into exercise research
4:20. How to utilize resistance training for hypertrophy vs strength
9:45. Dissociations between hypertrophy and strength with resistance training
15:35. Why changes in muscle size may not effect strength
17:55. Specificity of training and strength
19:35. What is blood flow restriction (BFR) and why do it?
21:28. BFR and aerobic/endurance exercise
23:25. The history of BFR and exercise research
27:45. How much pressure is applied during BFR to reduce the blood flow?
31:50. Discomfort from BFR
34:15. % of 1RM to use during BFR
35:22. Comparing resistance training with and without BFR
37:58. BFR and rehabilitation
41:00. Using BFR to train harder?
43:57. How common is BFR?
45:30. Do some use BFR to not have to train as hard?
46:41. What does BFR feel like? Uncomfortable?
48:06. Mechanisms that BFR during exercise has its effects
52:43. BFR, resistance training and muscle fibre recruitment
56:24. Hypoalgesia: reduced pain during and after exercise
1:01:31. Safety issues and BFR? Muscle damage, blood clots, blood pressure?
1:07:52. Relationship between muscle mass and strength
1:09:44. Hormonal responses to BFR and resistance training
1:11:50. Muscle signaling with BFR and resistance training
1:13:50. Protein synthesis with BFR and resistance training
1:14:40. Endurance exercise and BFR
1:18:00. Ischemia preconditioning
1:20:50. Cost of BFR systems etc
1:25:20. Effects of BFR on endothelium dysfunction or veins?
1:28:38. Any sex differences with BFR and resistance training
1:32:50. Strength training one arm affects the other arm
1:39:08. Do men and women have the same strength per muscle size?
1:43:56. Hand grip in kids as a biomarker
1:46:24. Career challenges etc
1:50:50. Takeaway messages
1:54:43. Outro (9 seconds)
Inside Exercise brings to you the who's who of research in exercise metabolism, exercise physiology and exercise’s effects on health. With scientific rigor, these researchers discuss popular exercise topics while providing practical strategies for all.
The interviewer, Emeritus Professor Glenn McConell, has an international research profile following 30 years of Exercise Metabolism research experience while at The University of Melbourne, Ball State University, Monash University, the University of Copenhagen and Victoria University.
He has published over 120 peer reviewed journal articles and recently edited an Exercise Metabolism eBook written by world experts on 17 different topics (https://link.springer.com/book/10.1007/978-3-030-94305-9).
Connect with Inside Exercise and Glenn McConell at:
Twitter: @Inside_exercise and @GlennMcConell1
Instagram: insideexercise
Facebook: Glenn McConell
LinkedIn: Glenn McConell https://www.linkedin.com/in/glenn-mcconell-83475460
ResearchGate: Glenn McConell
Email: [email protected]
Subscribe to Inside exercise:
Spotify: shorturl.at/tyGHL
Apple Podcasts: shorturl.at/oFQRU
YouTube: https://www.youtube.com/@insideexercise
Anchor: https://anchor.fm/insideexercise
Google Podcasts: shorturl.at/bfhHI
Anchor: https://anchor.fm/insideexercise
Podcast Addict: https://podcastaddict.com/podcast/4025218
Not medical advice

Dr Glenn McConell chats with Professor David Wright from the University of British Columbia, Canada. He has undertaken a lot of important work on the effect of exercise on muscle glucose uptake and mitochondria and then has branched out to examine the effect of exercise training on mitochondria in adipose tissue (fat). We discussed his work around that and then talked about an interesting new focus of his work around the metabolic effects of antipsychotics. He is finding that exercise can prevent the acute blood glucose raising effects of antipsychotics. A very interesting chat.
0:00. Introduction and how David got into research
6:10. His transition from muscle to fat research
10:05. Exercise activates AMPK in muscle and fat
10:57. Adipose tissue breakdown during exercise
13:58. Adrenaline/epinephrine
15:28. Exercise training effects on fat mitochondria
21:00. Why so much fat turnover during exercise
24:00. Fat use during ex in lean vs obese
26:25. Adrenaline regulation of fat adaptations to ex training
29:50. AMPK regulation of fat
32:05. Cross talk between organs during exercise
34:55. White, beige, brown adipose tissue
39:00. Human vs rodents brown adipose tissue
44:25. Adipokines and exercise training
48:40. Ectopic fat
49:40. Antipsychotics, obesity and diabetes
51:15. Each dose of an antipsychotic increases blood glucose
53:00. Exercise prevents these glucose effects of antipsychotics
59:00. GLP-1, glucagon and antipsychotics
1:03:20. Poor exercise adherence, do fasting instead?
1:05:15. Ketogenic diets and antipsychotics
1:08:50. Ketogenic diets and mental health
1:11:03. Clinicians awareness etc.
1:12:45. Sex and age differences
1:15:00. Acute vs chronic effects
1:15:40. Takeaway messages
1:19:27. Outro (9 seconds)
Inside Exercise brings to you the who's who of research in exercise metabolism, exercise physiology and exercise’s effects on health. With scientific rigor, these researchers discuss popular exercise topics while providing practical strategies for all.
The interviewer, Emeritus Professor Glenn McConell, has an international research profile following 30 years of Exercise Metabolism research experience while at The University of Melbourne, Ball State University, Monash University, the University of Copenhagen and Victoria University.
He has published over 120 peer reviewed journal articles and recently edited an Exercise Metabolism eBook written by world experts on 17 different topics (https://link.springer.com/book/10.1007/978-3-030-94305-9).
Connect with Inside Exercise and Glenn McConell at:
Twitter: @Inside_exercise and @GlennMcConell1
Instagram: insideexercise
Facebook: Glenn McConell
LinkedIn: Glenn McConell https://www.linkedin.com/in/glenn-mcconell-83475460
ResearchGate: Glenn McConell
Email: [email protected]
Subscribe to Inside exercise:
Spotify: shorturl.at/tyGHL
Apple Podcasts: shorturl.at/oFQRU
YouTube: https://www.youtube.com/@insideexercise
Anchor: https://anchor.fm/insideexercise
Google Podcasts: shorturl.at/bfhHI
Anchor: https://anchor.fm/insideexercise
Podcast Addict: https://podcastaddict.com/podcast/4025218
Not medical advice

Dr Glenn McConell chats with Professor Karyn Esser from the University of Florida, USA. She is an authority on circadian biology. We discuss whether exercise affects muscle circadian clocks and whether muscle clocks affect exercise. What is the best time to exercise and to eat etc. Also the effects of jet lag and shift work and how to best manage these. A very interesting chat. Karyn’s Twitter: @kaesser.
0:00. Introduction
2:30. How Karyn got into exercise research.
4:40. She was “picked up” by Arnold Schwarzenegger
5:32. Her muscle hypertrophy work
7:00. What are circadian rhythms?
9:40. Jet lag
11:10. How central clocks and peripheral clocks interact
14:16. Social jet lag
15:45. Timing of running rodents because nocturnal
16:47. Best to wear sunglasses when jet lagged?
17:54. Melatonin
19:40. Muscle clocks prepare the muscle
26:54. Sleep onset and dark onset are not necessarily correlated
30:23. Time of day and exercise performance
34:10. Running in the morning can shift muscle clocks forward
37:00. Train at the time of the race
39:25. Contracting muscle cells and circadian rhythms
41:00. Timing of eating and muscle circadian rhythms
43:00. How long does it take to shift clocks/jet jag
45:10. Exercise: morning people vs evening people
47:58. Stronger in the afternoon
50:30. Shift work and eating during the night
54:30. Best to do rotating or constant routine shift work?
55:57. Best time to exercise if shift worker?
57:55. Clocks are disrupted in diabetes
1:00:00. Researchers need to consider circadian rhythms
1:03:42. Is there circadian rhythm cross talk between organs?
1:06:03. Inflammation, muscle and circadian rhythms
1:08:12. The heart and circadian rhythms
1:11:30. Bone-muscle cross talk and circadian rhythms
1:13:28. Sex differences and circadian rhythms
1:15:00. Applicability of mouse studies to humans
1:16:42. Controversies in the field
1:17:52. Takeaway messages
1:20:12. Outro (9 seconds)
Inside Exercise brings to you the who's who of research in exercise metabolism, exercise physiology and exercise’s effects on health. With scientific rigor, these researchers discuss popular exercise topics while providing practical strategies for all.
The interviewer, Emeritus Professor Glenn McConell, has an international research profile following 30 years of Exercise Metabolism research experience while at The University of Melbourne, Ball State University, Monash University, the University of Copenhagen and Victoria University.
He has published over 120 peer reviewed journal articles and recently edited an Exercise Metabolism eBook written by world experts on 17 different topics (https://link.springer.com/book/10.1007/978-3-030-94305-9).
Connect with Inside Exercise and Glenn McConell at:
Twitter: @Inside_exercise and @GlennMcConell1
Instagram: insideexercise
Facebook: Glenn McConell
LinkedIn: Glenn McConell https://www.linkedin.com/in/glenn-mcconell-83475460
ResearchGate: Glenn McConell
Email: [email protected]
Subscribe to Inside exercise:
Spotify: shorturl.at/tyGHL
Apple Podcasts: shorturl.at/oFQRU
YouTube: https://www.youtube.com/@insideexercise
Anchor: https://anchor.fm/insideexercise
Google Podcasts: shorturl.at/bfhHI
Anchor: https://anchor.fm/insideexercise
Podcast Addict: https://podcastaddict.com/podcast/4025218
Not medical advice

Dr Glenn McConell chats with Professor David Bishop from Victoria University in Melbourne, Australia. He has a broad background in exercise physiology research and has focused for many years on exercise and muscle mitochondria. He finds that low volume, prolonged exercise tends to increase mitochondrial volume more than mitochondrial function while sprint exercise training does the opposite, increasing mitochondrial function more than mitochondrial volume. He hypothesizes that polarized type training may be best to get increases in both mitochondrial function and mitochondrial volume. A very interesting chat. David’s Twitter: @BlueSpotScience
0:00. Introduction
2:45. Defining the different training zones
4:30. More to being an endurance athlete than the mitochondria
6:15. Intensity vs volume for mitochondrial responses
8:30. Dissociations between mito function and mito volume
10:35. Mechanisms involved?
Takeaway messages
12:05. Issues with normalizing mitochondrial findings?
15:20. Applying results at rest, in recovery to during exercise
18:00. Isolated mito results correlate with NMR?
18:50. Polarized training best to get both mito function and volume?
23:30. Can’t assume signaling etc changes affect performance
27:35. Determinants of exercise performance
28:50. Lactate threshold and mitochondrial function
32:15. Training volume most important for mito content
33:20. Overtraining vs energy deficit
36:05. Should tailor training based on VO2 max?
38:35. VO2 max vs lactate threshold
40:00. VO2 max and running economy not linked?
44:20. Resting vs maximum heart rate
45:45. Sodium bicarbonate, lactate, training and mitochondria
49:46. Is training specificity overrated?
55:15. Interval training work: rest ratios
58:20. High intensity interval training and mito damage
1:01:30. Need lab testing?
1:05:10. Important to be concerned about training zones?
1:07:55. Tends to be in polarized training camp
1:11:55. Considering the needs/physiology of the event/sport
1:15:30. Takeaway messages
Outro (9 seconds)
1:17:10. Dividing the mito function per mg of muscle
1:21:15. Outro (9 seconds)
Inside Exercise brings to you the who's who of research in exercise metabolism, exercise physiology and exercise’s effects on health. With scientific rigor, these researchers discuss popular exercise topics while providing practical strategies for all.
The interviewer, Emeritus Professor Glenn McConell, has an international research profile following 30 years of Exercise Metabolism research experience while at The University of Melbourne, Ball State University, Monash University, the University of Copenhagen and Victoria University.
He has published over 120 peer reviewed journal articles and recently edited an Exercise Metabolism eBook written by world experts on 17 different topics (https://link.springer.com/book/10.1007/978-3-030-94305-9).
Connect with Inside Exercise and Glenn McConell at:
Twitter: @Inside_exercise and @GlennMcConell1
Instagram: insideexercise
Facebook: Glenn McConell
LinkedIn: Glenn McConell https://www.linkedin.com/in/glenn-mcconell-83475460
ResearchGate: Glenn McConell
Email: [email protected]
Subscribe to Inside exercise:
Spotify: shorturl.at/tyGHL
Apple Podcasts: shorturl.at/oFQRU
YouTube: https://www.youtube.com/@insideexercise
Anchor: https://anchor.fm/insideexercise
Google Podcasts: shorturl.at/bfhHI
Anchor: https://anchor.fm/insideexercise
Podcast Addict: https://podcastaddict.com/podcast/4025218
Not medical advice