Inside Exercise

Inside Exercise

By Glenn McConellHealth & FitnessFitness
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Inside Exercise episodes

  • #40 - The history of endurance training methods with Dr Michael Joyner

    Dr Glenn McConell chats for a second time with Professor Michael Joyner from the Mayo Clinic, Minnesota, USA. Michael blew me away with his absolutely amazing knowledge on past athletes and coaches and their endurance training methods. Very different types of training can result in similar results. His running Haiku: Run a lot of miles, some faster than your race pace, rest once in a while. Michael was first on the podcast on October 9th, 2022. Michael’s Twitter: @DrMJoyner

    0:00. Introduction
    2:25. Foot races in the 1700s and 1800s (running 5 min/mile!)
    3:56. Pheidippides: run from Marathon to Athens etc
    4:49. Tarahumara Indians from Northern Mexico
    5:05. Arthur Lydiard’s (Peter Snell etc) training methods
    7:45. Rudolf Harbig, Zatopek, Percy Cerutty, Herb Elliot
    9:50. Bob Schul (intervals twice a day) and Ron Clarke
    10:05. All roads lead to the 1964 5000m at the Tokyo Olympics
    11:35. Dellinger/Bowerman: Mixed training methods like today.
    13:10. Very different types of training can result in similar results
    13:30. His running Haiku: Run a lot of miles, some faster than your race pace, rest once in a while
    15:30. Kipchoge training very similar to Bill Rodgers and Frank Short (1970s)
    16:13. Derek Clayton: high mileage at close to race pace
    19:02. Several ways to reach the same VO2 max, LT and economy
    21:48. Long slow distance runners raced a lot. Eg Ed Winrow
    23:35. Year round training: Parvo Nurmi etc
    24:20. Glenn Cunningham: intervals. Rudolf Harbig
    26:01. Sweden during WWII, Zatopek interval training
    27:16. In the 60s push back against intervals, LSD
    29:12. Swimmers: Igloi style interval training with short recoveries
    32:35. Would runners do better with a modified Igloi/Schul style program?
    35:05. Michael’s impressive cycling training/ hard-easy
    39:02. “Peloton art”/ “Strava art”
    39:27. David Costill: reduced swimmers training volume
    43:17. How high a VO2 max can the average person attain?
    45:46. Arthur Lydiard/all round athletes etc
    48:37. Develop as all round athletes before specialize
    50:00. Overreaching/Overtraining
    52:40. Takeaway messages
    53:54. Outro (9 secs)
    Inside Exercise brings to you the who's who of research in exercise metabolism, exercise physiology and exercise’s effects on health. With scientific rigor, these researchers discuss popular exercise topics while providing practical strategies for all.
    The interviewer, Emeritus Professor Glenn McConell, has an international research profile following 30 years of Exercise Metabolism research experience while at The University of Melbourne, Ball State University, Monash University, the University of Copenhagen and Victoria University.
    He has published over 120 peer reviewed journal articles and recently edited an Exercise Metabolism eBook written by world experts on 17 different topics (https://link.springer.com/book/10.1007/978-3-030-94305-9).

    Connect with Inside Exercise and Glenn McConell at:
    Twitter: @Inside_exercise and @GlennMcConell1
    Instagram: insideexercise
    Facebook: Glenn McConell
    LinkedIn: Glenn McConell https://www.linkedin.com/in/glenn-mcconell-83475460
    ResearchGate: Glenn McConell
    Email: [email protected]
    Subscribe to Inside exercise:
    Spotify: shorturl.at/tyGHL
    Apple Podcasts: shorturl.at/oFQRU
    YouTube: https://www.youtube.com/@insideexercise
    Anchor: https://anchor.fm/insideexercise
    Google Podcasts: shorturl.at/bfhHI
    Anchor: https://anchor.fm/insideexercise
    Podcast Addict: https://podcastaddict.com/podcast/4025218
    Not medical advice

    55 min
  • #39 - Why muscle glycogen is important with Dr Niels Ørtenblad

    Dr Glenn McConell chats with Professor Niels Ørtenblad from the University of Southern Denmark. He is an expert on muscle glycogen. We discussed the history of muscle glycogen and exercise research, the effect of diet and exercise training on muscle glycogen levels and use, the distribution and use of muscle glycogen within different muscle fibre compartments, unusual to fully deplete muscle glycogen during exercise
    and the potential role of muscle glycogen depletion in muscle fatigue. Very interesting stuff. Niel’s Twitter: @nortenblad.
    0:00. Introduction and Niels background
    6:15. History of the study of muscle glycogen and exercise
    9:15. Muscle glycogen and lactate
    11:38. Correlation does not imply causation
    12:10. Fat use during exercise is less efficient than CHO
    14:12. Diet, muscle glycogen and exercise performance
    16:00. 1920s and 1930s a golden age of exercise physiology
    18:20. Bengt Saltin undertook 30,000 muscle biopsies
    20:00. Effect of intensity and duration on muscle glycogen use
    21:20. Diet and muscle glycogen use
    23:15. High glycogen results in high glycogen use during ex
    24:33. Exercise training results in higher muscle glycogen levels
    25:51. Why “waste” muscle glycogen when it’s high
    27:30. Energy faster from carbohydrate than from fat
    28:40. Carbohydrate ingestion and muscle glycogen use
    32:05. Glycogen particles / location within the muscle and fatigue
    36:51. Calcium release, glycogen levels and fatigue
    40:20. Unusual to fully deplete muscle glycogen during exercise
    42:40. Muscle glycogen depletion in different muscle fibers
    45:30. How muscle glycogen effects muscle calcium release
    49:55. How muscle glycogen effects muscle calcium uptake
    51:53. Muscle glycogen and excitation-contraction coupling
    57:18. Diabetes and muscle glycogen use during exercise
    58:17. Muscle glycogen use during exercise in male vs females
    59:24. Need really high muscle glycogen?/increases body weight
    1:04:16. Studies he’s excited to do
    1:05:38. Should try to disprove your hypothesis
    1:08:20. Takeaway messages
    1:09:30. Glycogen particle size with glycogen use/diet
    1:13:40. Outro (9 secs)
    Inside Exercise brings to you the who's who of research in exercise metabolism, exercise physiology and exercise’s effects on health. With scientific rigor, these researchers discuss popular exercise topics while providing practical strategies for all.
    The interviewer, Emeritus Professor Glenn McConell, has an international research profile following 30 years of Exercise Metabolism research experience while at The University of Melbourne, Ball State University, Monash University, the University of Copenhagen and Victoria University.
    He has published over 120 peer reviewed journal articles and recently edited an Exercise Metabolism eBook written by world experts on 17 different topics (https://link.springer.com/book/10.1007/978-3-030-94305-9).
    Connect with Inside Exercise and Glenn McConell at:
    Twitter: @Inside_exercise and @GlennMcConell1
    Instagram: insideexercise
    Facebook: Glenn McConell
    LinkedIn: Glenn McConell https://www.linkedin.com/in/glenn-mcconell-83475460
    ResearchGate: Glenn McConell
    Email: [email protected]
    Subscribe to Inside exercise:
    Spotify: shorturl.at/tyGHL
    Apple Podcasts: shorturl.at/oFQRU
    YouTube: https://www.youtube.com/@insideexercise
    Anchor: https://anchor.fm/insideexercise
    Google Podcasts: shorturl.at/bfhHI
    Anchor: https://anchor.fm/insideexercise
    Podcast Addict: https://podcastaddict.com/podcast/4025218

    1 hr 14 min
  • #39 - Do keto diets and ketone supplements make sense for exercise and health with Dr Jonathan Little

    Dr Glenn McConell chats with Professor Jonathan Little from University of British Columbia. Kelowna, Canada. He is an expert on metabolism, nutrition, type two diabetes and exercise. We discussed what are keto (ketogenic) diets, different types of keto diets, the rationale for them and their effect on heath and exercise performance. We then did the same with ketone supplements. Whether there is a rationale for keto diets depends on who you are (overweight vs lean, insulin sensitive vs T2D, athletes vs non athlete etc).


    0:00. Introduction and overview of the area
    3:38. Jonathan’s academic and sporting background
    6:58. Medical ketogenic “keto” diets and epilepsy
    9:07. Modern “well formulated” keto diets and metabolism
    13:15. What are ketone bodies
    15:46. Ketosis and adherence to keto diets (and other diets)
    20:04. Why/how keto diets reduce body weight
    22:49. Are glucose excursions (spikes) a problem?
    25:00. Effect of keto diets on cardiovascular risk/LDL etc
    27:56. Keto diets when lean vs overweight or have type 2 diabetes
    31:08. Cheat days when on keto diets
    34:44. Metabolic flexibility/adapting to different diets
    38:01. Keto diets and exercise metabolism/performance
    43:10. Energy not produced as quickly from fat vs CHO
    45:09. Endurance perf not better on keto diets vs high CHO diets
    47:00. Controversies re keto diets and ex perf
    49:25. Keto proponents arguments against high CHO
    51:25. If not an elite athlete probably don’t need to pack in CHO
    53:15. Keto may help overweight recreational sports people
    54:26. Long term keto diets and health
    57:07. CHO ingestion in keto adapted athletes
    59:06. Very low RERs in keto adapted during intense exercise
    1:02:30. Ketone supplements and exercise: types/rationale
    1:04:58. Ketone supplements and exercise performance
    1:07:58. Combined CHO plus ketone supplements and ex perf
    1:09:13. Combined keto diet plus ketone supplements and ex perf
    1:11:33. Ketone supplements and glucose tolerance/inflammation
    1:15:01. Ketone supplements before and during exercise
    1:15:58. Liver/beta cells and blood glucose regulation
    1:18:12. Takeaway messages
    1:23:23. Outro (9 secs)

    Inside Exercise brings the who's who of research in exercise metabolism, exercise physiology and exercise’s effects on health. With scientific rigor, these researchers discuss popular exercise topics while providing practical strategies for all.


    The interviewer, Emeritus Professor Glenn McConell, has an international research profile following 30 years of Exercise Metabolism research experience while at The University of Melbourne, Ball State University, Monash University, the University of Copenhagen and Victoria University.

    He has published over 120 peer reviewed journal articles and recently edited an Exercise Metabolism eBook written by world experts on 17 different topics (https://link.springer.com/book/10.1007/978-3-030-94305-9).

    Connect with Inside Exercise and Glenn McConell:

    Twitter: @Inside_exercise and @GlennMcConell1
    LinkedIn: Glenn McConell https://www.linkedin.com/in/glenn-mcconell-83475460
    ResearchGate: Glenn McConell

    Subscribe to Inside exercise:

    Spotify: shorturl.at/tyGHL
    Apple Podcasts: shorturl.at/oFQRU
    YouTube: https://www.youtube.com/@insideexercise

    Anchor: https://anchor.fm/insideexercise 

    Etc

    1 hr 24 min
  • #38 - Harassment, abuse and mental health in athletes with Dr Margo Mountjoy

    Dr Glenn McConell chats with Professor Margo Mountjoy from McMaster University in Canada. A wide ranging and at times emotional discussion about the types of harassment and abuse (psychological abuse underlies most), prevalence of abuse (higher in marginalized groups), power relationships, reporting policies and procedures, barriers to reporting abusive behavior, the Nasser case, how empower the good people to effect change etc. Trauma informed care, the 4Rs: Realising that trauma is common, recognizing the signs of trauma in other people, responding to it and resisting retraumatization. A very passionate, compassionate and caring person.


    0:00. Introduction and Margo’s sporting and Medical background
    6:25. How Margo was first confronted by abuse in sport
    8:25. Her leading IOC consensus statements on abuse
    10:35. Cultural normalization of abuse
    11:45. Barriers to reporting abusive behavior. Nasser case
    13:09. Safeguarding framework during the Olympic Games, local sport etc
    15:45. Types of harassment and abuse
    20:15. The Larry Nasser gymnasts sexual abuse case
    24:02. Toxic cultures, eg physical abuse of children in Japan
    25:35. Learned behaviors/positions of power
    29:21. Prevalence of abuse. Higher in marginalized groups
    34:30. Victimizing and sport training
    36:15. Homophobic slurs in sport
    38:37. Body fat, image, shaming/eating disorders
    42:15. RED-S (relative energy deficiency in sport)
    44:03. RED-S, weight loss and abuse
    45:37. Harassment, abuse and mental health
    48:39. Need to recognize, manage, treat and support
    53:12. Reportable offenses/involving the police
    54:25. Are things getting better?
    56:10. Doctors: Advocating/empowering
    57:44. Trauma informed care: the 4Rs.
    1:02:10. Takeaway messages
    1:04:10. Outro (9 secs)

    Inside Exercise brings to you the who's who of research in exercise metabolism, exercise physiology and exercise’s effects on health. With scientific rigor, these researchers discuss popular exercise topics while providing practical strategies for all.


    The interviewer, Emeritus Professor Glenn McConell, has an international research profile following 30 years of Exercise Metabolism research experience while at The University of Melbourne, Ball State University, Monash University, the University of Copenhagen and Victoria University.

    He has published over 120 peer reviewed journal articles and recently edited an Exercise Metabolism eBook written by world experts on 17 different topics (https://link.springer.com/book/10.1007/978-3-030-94305-9).

    Connect with Inside Exercise and Glenn McConell at:
    Twitter: @Inside_exercise and @GlennMcConell1
    Instagram: insideexercise
    Facebook: Glenn McConell
    LinkedIn: Glenn McConell https://www.linkedin.com/in/glenn-mcconell-83475460
    ResearchGate: Glenn McConell

    Subscribe to Inside exercise:

    Spotify: shorturl.at/tyGHL
    Apple Podcasts: shorturl.at/oFQRU
    YouTube: https://www.youtube.com/@insideexercise
    Anchor: https://anchor.fm/insideexercise
    Google Podcasts: shorturl.at/bfhHI

    Podcast Addict: https://podcastaddict.com/podcast/4025218

    1 hr 5 min
  • #37 - Exercise in the heat, dehydration, fluid ingestion and circulation with Dr José González-Alonso

    Dr Glenn McConell chats with Professor José González-Alonso from Brunel Univesity London. We discussed exercise in the heat, dehydration, fluid ingestion, blood flow, metabolism and human circulation. He has a very strong research track record having researched these areas for around 35 years. We discuss how he began his career doing research with some very big names.


    0:00. Introduction and how José got into research etc

    6:20. Does heat stress reduce muscle blood flow during exercise?

    8:20. Exercise in mild environmental conditions 

    11:20. Loss of bodily fluids during exercise 

    14:13. Heart rate and the periphery 

    16:35. Why cardiovascular drift during prolonged exercise? 

    19:23. Effect of dehydration on ex performance 

    23:50. Effects of fluid ingestion during exercise 

    31:00. Fluid ingestion, adrenaline and muscle glycogen use 

    33:30. Blood particles (osmolality), dehydration and exercise 

    36:28. Blood volume, cardiac output and VO2 max 

    41:30. Exercise in hot and humid conditions 

    44:24. Central (brain) causes of fatigue during exercise? 

    52:35. Generalizing results from non elite participants 

    53:40. Drinking during running vs cycling 

    56:37. Starting race euhydrated vs hypohydrated 

    57:50. Only drink a lot if sweating a lot /osmolality and urine 

    1:00:00. Sweat sodium concentration during exercise 

    1:02:25. What is still unknown in the area? 

    1:10:35. Heat, elite athletes and mitochondrial adaptations 

    1:15:40. Hypohydration vs dehydration and ex perf 

    1:17:31. Takeaway messages 

    1:21:50. Heat, ATP and blood flow 

    1:24:27. Outro (9 secs)

    Inside Exercise brings to you the who's who of research in exercise metabolism, exercise physiology and exercise’s effects on health. With scientific rigor, these researchers discuss popular exercise topics while providing practical strategies for all.


    The interviewer, Emeritus Professor Glenn McConell, has an international research profile following 30 years of Exercise Metabolism research experience while at The University of Melbourne, Ball State University, Monash University, the University of Copenhagen and Victoria University.

    He has published over 120 peer reviewed journal articles and recently edited an Exercise Metabolism eBook written by world experts on 17 different topics (https://link.springer.com/book/10.1007/978-3-030-94305-9).

    Connect with Inside Exercise and Glenn McConell at:
    Twitter: @Inside_exercise and @GlennMcConell1
    Instagram: insideexercise
    Facebook: Glenn McConell
    LinkedIn: Glenn McConell https://www.linkedin.com/in/glenn-mcconell-83475460
    ResearchGate: Glenn McConell

    Subscribe to Inside exercise:
    Spotify: shorturl.at/tyGHL
    Apple Podcasts: shorturl.at/oFQRU
    YouTube: https://www.youtube.com/@insideexercise
    Anchor: https://anchor.fm/insideexercise
    Google Podcasts: shorturl.at/bfhHI
    Anchor: https://anchor.fm/insideexercise
    Podcast Addict: https://podcastaddict.com/podcast/4025218

    1 hr 25 min
  • #36 - Effect of the menstrual cycle, oral contraception, pregnancy and the menopause on exercise performance with Dr Kirsty Elliott Sale

    Dr Glenn McConell chats with Professor Kirsty Elliott-Sale from Manchester Metropolitan University, England. She is an expert on female exercise physiology . We discuss the effects of the menstrual cycle, oral contraception, pregnancy and the menopause on exercise performance. As will become apparent, more research needs to be done on these important areas.


    0:00. Introduction and Kirsty’s intro to research etc
    5:05. Finally more research on female exercise physiology
    6:25. Men have been the default research participants
    9:53. Sex difference studies are a very different issue
    11:47. Effects of the menstrual cycle on exercise performance
    -Systematic review/meta analysis mentioned: Kelly Lee McNulty et al. Sports Med. 50(10):1813-1827, 2020.
    14:45. Variation in menstrual cycle length, existence, symptoms
    20:35. Manipulating the menstrual cycle/hormonal profile
    22:13. Ovarian hormone changes over the typical menstrual cycle
    24:40. Effect of oral contraception on ovarian hormone levels
    32:05. Effect of oral contraception on exercise performance
    -Systematic review/meta analysis mentioned: Elliott-Sale et al. Sports Med. 50(10): 1785–1812, 2020.
    42:00. Effects of pregnancy on exercise performance
    46:50. Questionnaires on these areas of research
    49:00. Return to exercise after having children
    55:30. Effect of the menopause on exercise performance
    1:02:40. Does the menopause effect the trajectory of changes
    1:04:17. Muscle mass loss after menopause
    1:05:35. What Kirsty is excited about at the moment
    1:08:30. Takeaway messages
    -Methodological considerations paper: Elliott-Sale. Sports Med. 51(5):843-861, 2021.
    1:11:19. Outro (9 secs)

    Inside Exercise brings to you the who's who of research in exercise metabolism, exercise physiology and exercise’s effects on health. With scientific rigor, these researchers discuss popular exercise topics while providing practical strategies for all.


    The interviewer, Emeritus Professor Glenn McConell, has an international research profile following 30 years of Exercise Metabolism research experience while at The University of Melbourne, Ball State University, Monash University, the University of Copenhagen and Victoria University.

    He has published over 120 peer reviewed journal articles and recently edited an Exercise Metabolism eBook written by world experts on 17 different topics (https://link.springer.com/book/10.1007/978-3-030-94305-9).

    Connect with Inside Exercise and Glenn McConell at:
    Twitter: @Inside_exercise and @GlennMcConell1
    Instagram: insideexercise
    Facebook: Glenn McConell
    LinkedIn: Glenn McConell https://www.linkedin.com/in/glenn-mcconell-83475460
    ResearchGate: Glenn McConell

    Subscribe to Inside exercise:

    Spotify: shorturl.at/tyGHL
    Apple Podcasts: shorturl.at/oFQRU
    YouTube: https://www.youtube.com/@insideexercise
    Anchor: https://anchor.fm/insideexercise
    Google Podcasts: shorturl.at/bfhHI
    Anchor: https://anchor.fm/insideexercise
    Podcast Addict: https://podcastaddict.com/podcast/4025218

    1 hr 12 min
  • #35 - Gaining muscle to combat losing muscle with Dr Stuart Phillips

    Dr Glenn McConell chats with Professor Stuart Phillips from McMaster University in Canada. He is the world expert on protein needs for optimal muscle mass with exercise. We discussed gaining muscle to combat losing muscle. The discussion centered around resistance training, dietary protein needs, whether need protein from meat, the timing of protein intake, the need for protein supplements and protein needs with aging. Lots more. He has been very open to changing his views based on the data. An important, fun chat.


    0:00. Introduction and Stuart’s research journey
    7:50. Gaining muscle to combat losing muscle
    10:35. Muscle mass loss with aging, role of inactivity
    12:30. Need to do both cardio and resistance training
    14:43. Maximizing gains in muscle
    18:25. Rating of perceived exertion to prescribe exercise
    22:25. Muscular endurance vs aerobic endurance
    26:20. Rugby: Big, fast and fit. Jonah Lomu
    27:55. Resistance training can increase running economy
    29:08. Now believes no need for most athletes to eat extra protein
    33:55. Aging results in anabolic resistance
    35:40. Timing of protein intake is not important
    36:35. Most don’t need protein supplements
    40:10. Need other supplements? Creatine
    44:28. Plant-based diets are sufficient for protein needs
    47:20. Healthy vegan/vegetarian diets and health
    49:08. Healthy vegan/vegetarian diets have sufficient protein
    52:39. Unhealthy vegan/vegetarian diets
    54:40. Protein synthesis rates vs long term outcome
    58:15. Can you outrun a bad diet?/issues with social media
    1:04:44. Protein turnover and complementary proteins etc.
    1:08:20. Genetic limit to muscle mass etc
    1:10:15. Leucine, anabolic steroids and protein synthesis
    1:13:15. Are there adverse effects of protein? Protein restriction
    1:17:00. Plant-based protein better for longevity
    1:19:30. Rodent studies/ catabolic crisis etc
    1:21:30. Why endurance athletes live longer than resistance athletes
    1:23:04. High load vs low load and hypertrophy
    1:24:32. Capillary blood flow and resistance training
    1:25:55. Interference of strength and endurance training?
    1:26:50. Takeaway messages
    1:31:15. Outro (9 secs)

    Inside Exercise brings to you the who's who of research in exercise metabolism, exercise physiology and exercise’s effects on health. With scientific rigor, these researchers discuss popular exercise topics while providing practical strategies for all.


    The interviewer, Emeritus Professor Glenn McConell, has an international research profile following 30 years of Exercise Metabolism research experience while at The University of Melbourne, Ball State University, Monash University, the University of Copenhagen and Victoria University.

    He has published over 120 peer reviewed journal articles and recently edited an Exercise Metabolism eBook written by world experts on 17 different topics (https://link.springer.com/book/10.1007/978-3-030-94305-9).

    Connect with Inside Exercise and Glenn McConell at:
    Twitter: @Inside_exercise and @GlennMcConell1
    Instagram: insideexercise
    Facebook: Glenn McConell
    LinkedIn: Glenn McConell https://www.linkedin.com/in/glenn-mcconell-83475460
    ResearchGate: Glenn McConell

    Subscribe to Inside exercise:

    Spotify: shorturl.at/tyGHL
    Apple Podcasts: shorturl.at/oFQRU
    YouTube: https://www.youtube.com/@insideexercise

    Anchor, Google podcasts Etc

    1 hr 32 min
  • #34 - The psychobiology of endurance performance with Dr Samuele Marcora
    Dr Glenn McConell chats with Professor Samuele Marcora from the University of Bologna in Italy. He is an expert on the psychobiology of endurance performance and fatigue. We discussed the importance of the perception of effort/rating of perceived exertion on exercise performance and fatigue. Pros and cons of zoning in vs zoning out. How the perception of effort can be modified by factors such as exercise training, mental fatigue and caffeine.  
    0:00. Introduction and Samuele’s research journey 
    8:33. Feeling of fatigue when at rest vs fatigue during exercise 
    11:03. “Central fatigue” 
    12:09. Fatigue and perception of effort 
    15:33. Doesn’t agree with the Central governor model 
    20:54. Motivation and exercise in the heat 
    23:08. RED-S, expectancy of perception of effort 
    24:46. Aspects making up the psychobiological model 
    29:55. Time trials and pacing 
    32:34. Mass start races 
    34:25. Pros and cons of zoning in vs zoning out 
    39:06. Amnesia and pacing 
    41:00. Caffeine reduces perception of effort 
    46:45. Physical fitness reduces perception of effort 
    50:40. In a marathon the perception of effort is similar for everyone 
    51:35. How do some push through pain vs mere mortals 
    55:58. Motivation and exercise performance 
    57:36. Experience and the ability to push oneself 
    59:50. SAS type training is essentially psychological training 
    1:01:19. Contribution of genetic components 
    1:02:36. Going too fast at the start of races 
    1:05:22. Central command vs feedback (afferent) signals 
    1:14:03. Respiratory frequency and perception of effort 
    1:15:58. Brain training/mental fatigue 
    1:20:35. Psychological load affects overall training load 
    1:25:03. Why fatigue when ingest carbohydrate 
    1:29:45. Dopamine /serotonin and fatigue 
    1:33:24. Capsaicin and perception of effort 
    1:35:05. Panadol (Paracetamol) and perception of effort 
    1:36:58. Pacemakers help partly due to cognitive drafting 
    1:38:32. Takeaway messages 
    1:40:25. What about efforts under 30 seconds? 
    1:45:02. Outro (9 secs)  
    Inside Exercise brings to you the who's who of research in exercise metabolism, exercise physiology and exercise’s effects on health. With scientific rigor, these researchers discuss popular exercise topics while providing practical strategies for all.  
    The interviewer, Emeritus Professor Glenn McConell, has an international research profile following 30 years of Exercise Metabolism research experience while at The University of Melbourne, Ball State University, Monash University, the University of Copenhagen and Victoria University.  
    He has published over 120 peer reviewed journal articles and recently edited an Exercise Metabolism eBook written by world experts on 17 different topics (https://link.springer.com/book/10.1007/978-3-030-94305-9).  
    Connect with Inside Exercise and Glenn McConell at: 
    Twitter: @Inside_exercise and @GlennMcConell1 
    Instagram: insideexercise 
    Facebook: Glenn McConell 
    LinkedIn: Glenn McConell https://www.linkedin.com/in/glenn-mcconell-83475460
    ResearchGate: Glenn McConell 
    1 hr 46 min
  • #33 - Fat metabolism, insulin resistance and exercise with Dr Graham Holloway

    Dr Glenn McConell chats with Professor Graham Holloway from the University of Guelph in Canada. He is an expert on mitochondrial bioenergetics. We discussed the effect of exercise intensity and duration and exercise training on fat/lipid and carbohydrate metabolism, whether alterations in substrate availability such as high fat diets, high fat meals, high carbohydrate meals etc affect fat oxidation and mitochondrial function and the effect of high fat diets on insulin sensitivity. Central role of ADP.


    0:00. Introduction and Graham’s sporting and research journey
    6:06. Fat availability and fat oxidation at rest snd during exercise
    8:40. Carbohydrate metabolism out-competes fat metabolism
    11:25. More energy per unit of oxygen from carbohydrate than fat
    13:13. Increased ability to oxidize fat with endurance training
    15:21. ADP and breakdown of muscle glycogen
    16:20. Less increase in ADP during exercise after ex training
    17:45. Effect of exercise intensity and duration on exercise metabolism
    23:46. Fat more efficient store of energy
    25:32. Does lactate inhibit fat oxidation?
    28:47. Exercise training and sparing muscle glycogen during ex
    29:40. Maximum fat oxidation rate
    31:40. Best intensity of exercise training for mitochondrial adaptations
    35:09. High fat diets and fat oxidation during exercise
    37:40. Randle cycle/Glucose-fatty cycle
    38:28. Meal composition affects what is used for energy
    40:06. Excess body lipids/fat contribute to insulin resistance
    45:35. Reactive oxygen species, fat and exercise
    49:03. Best way to remove excess lipids/fat is to exercise
    50:14. Dealing with extra carbohydrate
    51:25. One high fat meal can cause insulin resistance
    51:54. Insulin resistance and fat oxidation/ADP:
    53:15. People with T2D have normal fat oxidation and normal glucose uptake during exercise
    55:12. Does insulin resistance cause mitochondrial dysfunction?
    58:14. Does mitochondrial dysfunction cause insulin resistance?
    59:19. One high fat meal can cause insulin resistance
    1:00:43. Ex training protects against fat induced insulin resistance
    1:03:12. Acute exercise is protective w/o changing weight
    1:04:30. Same mechanisms in adipose tissue/heart as skeletal muscle
    1:06:04. Acute vs chronic reactive oxygen species/stress/exercise
    1:10:10. Controversy around mitochondrial dysfunction/insulin resistance
    1:11:42. Increasing fat oxidation by high fat diets
    1:14:17. Takeaway messages
    1:16:00. Outro (9 secs)

    Inside Exercise brings to you the who's who of research in exercise metabolism, exercise physiology and exercise’s effects on health. With scientific rigor, these researchers discuss popular exercise topics while providing practical strategies for all.

    The interviewer, Emeritus Professor Glenn McConell, has an international research profile following 30 years of Exercise Metabolism research experience while at The University of Melbourne, Ball State University, Monash University, the University of Copenhagen and Victoria University.

    He has published over 120 peer reviewed journal articles and recently edited an Exercise Metabolism eBook written by world experts on 17 different topics (https://link.springer.com/book/10.1007/978-3-030-94305-9).

    Connect with Inside Exercise and Glenn McConell at:

    Twitter: @Inside_exercise and @GlennMcConell1

    LinkedIn: Glenn McConell https://www.linkedin.com/in/glenn-mcconell-83475460


    Subscribe to Inside exercise:

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    1 hr 17 min
  • #32 - Carbohydrate metabolism during exercise with Dr Mark Hargreaves

    Dr Glenn McConell chats with Professor Mark Hargreaves from the University of Melbourne in Australia. He is a leader in exercise metabolism/physiology and was Glenn’s PhD supervisor. The discussion centred around the effects of muscle glycogen availability and carbohydrate (CHO) ingestion on exercise metabolism and also performance/fatigue. There was also discussion of  high fat/ketogenic diets, GLUT-4, the central nervous system and the effect of the volume of fluid ingested with and without addition of electrolytes.


    0:00. Introduction and Mark’s beginnings in exercise research
    9:10. Effect of exercise intensity on the fuel mix used
    12:27. High fat/keto diets and exercise metabolism/performance
    16:10. Hazards of too much fat or too much carbohydrate
    Also, what type of dietary fat and what type of dietary carbohydrate matters.
    18:40. Need personalized management of people
    21:05. Hard to keep muscle glycogen low
    24:32. Continuous glucose monitors
    25:30. Why use more glycogen during ex than need if start high?
    27:00. Heat and glycogen metabolism
    28:26. Why fatigue when consuming carbohydrate during ex?
    31:50. Carbohydrate ingestion and liver glucose output
    33:30. High doses of carbohydrate ingestion during exercise
    38:00. Need increased CHO availability if ex less than an hour?
    41:25. Repeated sprints and glycogen etc
    43:05. Resynthesis of glycogen during low intensity exercise?
    47:12. Both excess CHO and excess fat can cause problems
    52:35. Caffeine vs coffee and metabolism
    53:40. Rehydration with meals vs special solutions
    54:25. Fluid ingestion and electrolytes
    59:10. Glycogen and AMP-activated protein kinase (AMPK)
    1:00:50. Mark’s current senior academic position
    1:02:47. Mark’s “photographic memory” and the literature
    1:04:39. Exercise and GLUT-4 expression
    1:09:00. Muscle GLUT-4 normal in muscle in T2D
    1:10:23. Takeaway messages
    1:14:34. Outro (9 secs)

    Inside Exercise brings to you the who's who of research in exercise metabolism, exercise physiology and exercise’s effects on health. With scientific rigor, these researchers discuss popular exercise topics while providing practical strategies for all.


    The interviewer, Emeritus Professor Glenn McConell, has an international research profile following 30 years of Exercise Metabolism research experience while at The University of Melbourne, Ball State University, Monash University, the University of Copenhagen and Victoria University.

    He has published over 120 peer reviewed journal articles and recently edited an Exercise Metabolism eBook written by world experts on 17 different topics (https://link.springer.com/book/10.1007/978-3-030-94305-9).

    Connect with Inside Exercise and Glenn McConell at:
    Twitter: @Inside_exercise and @GlennMcConell1
    Instagram: insideexercise
    Facebook: Glenn McConell
    LinkedIn: Glenn McConell https://www.linkedin.com/in/glenn-mcconell-83475460
    ResearchGate: Glenn McConell

    Subscribe to Inside exercise:

    Spotify: https://open.spotify.com/show/3pSYnNSXDkNLH8rImzotgP?si=Whw_ThaERF6iIKwxutDoNA
    Apple Podcasts: https://podcastsconnect.apple.com/my-podcasts/show/inside-exercise/03a07373-888a-472b-bf7e-a0ff155209b2

    YouTube: https://www.youtube.com/@insideexercise

    Anchor, Google podcasts, Podcast addict etc

    1 hr 15 min

About Inside Exercise

From the publisher's feed

Inside Exercise brings the absolute who's who of researchers in exercise physiology and metabolism and exercise’s effects on health. With scientific rigor, these researchers discuss popular exercise topics while providing practical strategies for all.

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