One of the most significant revolutions in science is underway, and yet most people haven't even heard of it. It's called CRISPR, and it is an easy, inexpensive process for cutting and pasting DNA - the code of life.  It is already being used in human trials to cure genetic disease, and it promises to transform agriculture, with drought-resistant crops that will better feed the world.  But it also threatens to usher in a frightening era of designer babies and unintended consequences.  The two lead scientists behind CRISPR, Jennifer Doudna and Feng Zhang, talk here about their lives and their research, and they sound the alarm about the dangers of their own discovery.
(c ) American Academy of Achievement 2019

Jennifer Doudna and Feng Zhang: The Code of Life

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Jeff Koons is one of the most successful artists of our time. For 40+ years, his iconic works have brought a sense of playfulness to museums worldwide, and sometimes a bit of controversy as well. His iconic pop art sculptures include a giant pink rabbit that looks so remarkably like a shiny mylar inflatable, it's hard to believe it is made of metal. His balloon dog, the type you'd see at a child's birthday party, likewise demands a second look. In this recent interview, Koons describes his lifelong love of gazing balls, like the ones he saw growing up in York, Pennsylvania, and how he came to incorporate them (and other reflective surfaces) into his art. He talks about his days as a young, aspiring artist, and his unlikely meeting with Salvador Dalí.  And  he talks about what's next, as he prepares to launch his latest pieces into space.

Jeff Koons: Contemporary Art Phenomenon

The COVID-19 vaccine came out at warp speed because of the work of these two scientists. This week, they were awarded the Nobel Prize in Physiology or Medicine. In celebration, we are re-posting our episode about Katalin Karikó and Drew Weissman. For many, many years they investigated the secrets of messenger RNA (mRNA).  And when the pandemic began, their research was ready and waiting. On this episode you’ll hear Katalin Karikó talk about her humble beginnings in Hungary, and the forces that enabled her to persevere, even though for decades people thought her ideas about mRNA were laughable.  She was denied grants, lost jobs and wasn’t taken seriously, but she never wavered. Fortunately, she met Drew Weissman one day at a copy machine, where they both worked at the University of Pennsylvania. Dr. Weissman was an immunologist, working on a vaccine for HIV.  He was interested in Karikó’s work and they began to collaborate. Even when they made major discoveries, they could not get support for their work… until the Corona Virus appeared. Now the scientific world sees the potential that Karikó and Weissman saw all along: that mRNA may open the door to many other vaccines and to therapeutic treatment for a host of illnesses, from Cancer to Sickle Cell Anemia to Heart Disease. 
(c ) American Academy of Achievement 2023

Best of (Nobel Prize Edition) - Katalin Karikó and Drew Weissman: The Vaccine Revolution

Gordon Lightfoot has died, at the age of 84. He spoke with the Academy of Achievement last year, and we featured that interview in an episode. To honor the legendary singer and songwriter, we are re-posting the episode today. 

Gordon Lightfoot had a slew of international hits in the 1960's and 70's, including "If You Could Read My Mind," "Sundown" and The Wreck of the Edmund Fitzgerald." His songs were also performed by some of the biggest stars of that time, including Jerry Lee Lewis, The Grateful Dead, Elvis Presley, Bob Dylan, and Barbra Streisand.  Lightfoot was still writing and performing into his 80's. In this interview you will find him as charming a raconteur as you might expect, given the nature of the songs he writes. He talks about his childhood in a small town in Ontario, and about his path to the top of the music industry. He describes the quirks of his songwriting process, and explains why he changed the words of "Edmund Fitzgerald" after he recorded it. 

(c ) American Academy of Achievement 2022-2023

Best Of - Gordon Lightfoot: If You Could Read My Mind

These two Pulitzer Prize-winning biographers have spent their careers delving into the lives of Americans who changed the course of U.S. history. T.J. Stiles and David Blight talk here about how historical biography can bring us closer to an understanding of the times we live in. They discuss why Jesse James, General George Custer, Cornelius Vanderbilt and Frederick Douglass are relevant still. And they let us in on some surprising aspects of their own lives! 

© American Academy of Achievement 2023

T.J. Stiles and David Blight: The Epic Life

Wayne Shorter was a legendary saxophonist and composer whose career began in the 1950's and spanned the development of modern jazz. Mr. Shorter died this week, at the age of 89. To honor his life and music, we are bringing back this episode, which originally aired in 2017. It features Wayne Shorter and a jazz artist 50 years his junior: Esperanza Spalding. Ms. Spalding is a bass player, composer, lyricist and singer - and one of the most exciting artists in contemporary jazz. Wayne Shorter and Esperanza Spalding may have come of age during different jazz eras and in different parts of the country, but they became friends and artistic soulmates, who shared many of the same views about making music and the creative process.

(c ) American Academy of Achievement 2017-2023

Jennifer Doudna and Feng Zhang: The Code of Life

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