Journal Club series presented by CGA-IGC

This episode is hosted by Dr. Thomas Slavin (T.J.) and features Amy K. Otto, PhD, who is a Research Assistant Professor in the Department of Public Health Sciences at the University of Miami Miller School of Medicine.  Together they discuss the article “Impact of Patients' Companions on Clinical Encounters Between Black Patients and Their Non-Black Oncologists,” which was published in JCO Oncology Practice and found here: https://pubmed.ncbi.nlm.nih.gov/33411574/ This episode was recorded on August 26, 2021 and reflects expert opinion at the time of the recording.

This episode is hosted by Dr. Thomas Slavin (T.J.) and features Rachel Pearlman, MS, CGC, who is a Licensed, Certified Genetic Counselor and Assistant Professor in the Department of Internal Medicine at The Ohio State University Comprehensive Cancer Center. Together they discuss the article “Prospective Statewide Study of Universal Screening for Hereditary Colorectal Cancer: The Ohio Colorectal Cancer Prevention Initiative,” which was published in JCO Precision Oncology and found here: https://pubmed.ncbi.nlm.nih.gov/34250417/This episode was recorded on August 10, 2021 and reflects expert opinion at the time of the recording.

This episode is hosted by Dr. Thomas Slavin (T.J.) and features Dr. Eduardo Vilar-Sanchez. Dr. Vilar-Sanchez is a medical oncologist at MD Anderson Cancer Center. Together they discuss “Naproxen chemoprevention promotes immune activation in Lynch syndrome colorectal mucosa,” which was published in Gut and found here: https://pubmed.ncbi.nlm.nih.gov/32641470/

This episode was recorded on March 26, 2021 and reflects expert opinion at the time of the recording.

This episode is hosted by Dr. Thomas Slavin (T.J.) and features Dr. Bryson Katona and Dr. Suzanne MacFarland. Dr. Katona is a gastroenterologist at Penn Medicine and Dr. MacFarland is an oncologist in the Children’s Hospital of Philadelphia. Together they discuss their recent publication, “Phenotypic Differences in Juvenile Polyposis Syndrome With or Without a Disease-causing SMAD4/BMPR1A Variant,” published in Cancer Prevention Research and found here: https://pubmed.ncbi.nlm.nih.gov/33097490/

This episode was recorded on January 25, 2021 and reflects expert opinion at the time of the recording.

This episode is hosted by Dr. Thomas Slavin (T.J.) and features Dr. Carol Burke, a gastroenterologist at the Cleveland Clinic. They discuss a study of combination therapy to delay disease progression in patients with familial adenomatous polyposis, recently published in The New England Journal of Medicine, found here: https://pubmed.ncbi.nlm.nih.gov/32905675/

This episode was recorded on January 12, 2021 and reflects expert opinion at the time of the recording.

The sixth episode, hosted by Dr. TJ Slavin, features Dr. Sonia Kupfer, a gastroenterologist at University of Chicago and former CGA-IGC president. They discuss the updated clinical practice guidelines for hereditary diffuse gastric cancer that were recently published online in Lancet Oncology, found here: https://pubmed.ncbi.nlm.nih.gov/32758476/ .

This episode was recorded on September 21, 2020, and reflects expert opinion at the time of the recording.

The fifth episode, hosted by CGA-IGC Council Member Dr. Swati Patel, features Sir John Burn, who is a professor of clinical genetics at Newcastle University, and Dr. Toni Seppälä, who is a GI surgeon from University of Helsinki currently conducting a research fellowship at Johns Hopkins University. They discuss recently updated data from the CAPP2 study of aspirin chemoprevention in individuals with Lynch syndrome that was published in Lancet this summer, found here: https://pubmed.ncbi.nlm.nih.gov/32534647/.

This episode was recorded on September 22, 2020, and reflects expert opinion at the time of the recording.

This episode is hosted by Dr. Leah Biller and features Dr. Zsofia Stadler, a medical oncologist at Memorial Sloan Kettering Cancer Center and CGA council member, and Dr. Michael Hall, a medical oncologist at Fox Chase Cancer Center and CGA past president. They discuss data from Abstract 1500 (https://meetinglibrary.asco.org/record/185963/abstract), which reports on targeted therapy based on germline analysis of tumor-normal sequencing in a pan-cancer population, as well as data from the plenary presentation about the clinical trial KEYNOTE-177 (https://meetinglibrary.asco.org/record/186928/abstract), a study of pembrolizumab versus standard therapy for treatment of MSI-H metastatic colorectal cancer.

This episode was recorded on August 28, 2020 and reflects expert opinion at the time of the recording.

The third episode, hosted by CGA-IGC Council Member Dr. Swati Patel, features Dr. Arne Bleijenberg, who is a research fellow at Amsterdam University Medical Center, and Dr. Evelien Dekker, who is a professor in the Department of Gastroenterology & Hepatology and Gastrointestinal Oncology and the head of the Hereditary Cancer Center at the Amsterdam University Medical Center. They discuss the recently updated World Health Organization Guidelines on diagnosis of Serrated Polyposis Syndrome (SPS) (summarized here https://pubmed.ncbi.nlm.nih.gov/31982410/). Dr. Bleijenberg and Dr. Dekker also discuss their recent publications that shed light on a personalized approach to surveillance in SPS (https://pubmed.ncbi.nlm.nih.gov/30981990/) and long-term outcomes and natural disease course in those with SPS undergoing colonoscopic surveillance (https://pubmed.ncbi.nlm.nih.gov/32360902/). This episode was recorded on July 9, 2020 and reflects expert opinion at the time of the recording.

The second episode features Dr. Leah Biller, CGA education committee member, who is interviewed by fellow CGA education committee member TJ Slavin. They discuss "A Multi-Institutional Cohort of Therapy-Associated Polyposis in Childhood and Young Adulthood Cancer Survivors", recently published online in Cancer Prevention Research. You can find the article here: https://www.ncbi.nlm.nih.gov/pubmed/32051178

This episode was recorded May 5, 2020 and reflects expert opinion at the time of the recording.