Go online to PeerView.com/KEW860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. Early intervention is central to reducing excess weight gain and the risk of obesity-related comorbidities, yet many people never receive a formal diagnosis or specialty obesity care. With this in mind, how can clinicians best support this patient population? Endocrinologists, in particular, are on the front lines of managing and treating this complex disease. In this PeerView inReview, an expert uses patient videos to explain what you need to know about effective, compassionate patient communication and offers practical guidance on how to best integrate anti-obesity medications into patient care to improve long-term outcomes. Upon completion of this activity, participants should be better able to: Prioritize obesity as a chronic, progressive disease that requires individualized, long-term management; Initiate nonjudgmental conversations with individuals living with obesity and engage in effective shared decision-making discussions to achieve sustained weight loss; Compare the mechanism of action, efficacy, and safety of approved and emerging medications for the long-term management of obesity; and Identify people with obesity who could benefit from treatment with anti-obesity medications