For thousands of years, we've searched to answer the question: Who are we? Today, science has brought us closer than ever to the answer. This hour, TED speakers share ideas on what makes us ... us. In a brand new interview, neuroscientist Anil Seth explores how our brains construct our conscious reality--everything we perceive, from objects to emotions. Other guests from the original 2016 episode include biochemist Sam Sternberg, psychologist Steven Pinker, and humorist Ze Frank.

Cities are symbols of hope and opportunity. But today, overcrowding and gentrification are hurting their most vulnerable residents. This hour, TED speakers explore how we can build more humane cities. Guests include architects Liz Ogbu and Vishaan Chakrabarti, writer OluTimehin Adegbeye, former Albuquerque Mayor Richard Berry, and journalist Drew Philp.

Original broadcast date: February 10, 2017. We expect a lot of our doctors, but they don't always have the best tools to treat us. This episode, TED speakers explore new ways to think about disease, diagnosis, and the delicate art of healing. Guests include filmmaker Jennifer Brea, anesthesiologist Elliot Krane, law professor Dorothy Roberts, and cardiologist Paula Johnson.

Original broadcast date: March 10, 2017. Whether you're choosing spaghetti sauce or a life partner, making decisions can be paralyzing. This hour, TED speakers explore how we make the choices we make, and how we learn to live with them. Guests include author Malcolm Gladwell, psycho-economist Sheena Iyengar, philosopher Ruth Chang, and behavioral economist Dan Ariely.

Is there a way to talk about death candidly, without fear ... and even with humor? How can we best prepare for it with those we love? This hour, TED speakers explore the beauty of life ... and death. Guests include lawyer Jason Rosenthal, humorist Emily Levine, banker and travel blogger Michelle Knox, mortician Caitlin Doughty, and entrepreneur Lux Narayan.

What lies beyond the reach of the naked eye, and how do these hidden forces shape our lives? This hour, TED speakers reveal forgotten cities, underwater canyons, tiny parasites, and a boiling river. In a special updated interview, space archaeologist Sarah Parcak explains how a global team of citizen scientists has helped her discover thousands of ancient hidden sites. Other guests from the original 2016 episode include computer scientist Abe Davis, ocean explorer Robert Ballard, science writer Ed Yong, and geoscientist Andrés Ruzo.

Design is all around us, but much of it could be better, bolder, more elegant. This episode, TED speakers on the essence of good design in buildings, brands, the digital realm and the natural world. Guests include designer Tony Fadell, architect Marc Kushner, Airbnb co-founder Joe Gebbia, design critic Alice Rawsthorn, and science writer Janine Benyus. (Original broadcast date: May 20, 2016).

Is life today better than ever before? Does the data bear that out? This hour, TED speakers explore the stories we tell with numbers — and whether those stories portray the full picture. Guests include psychologist Steven Pinker, economists Tyler Cowen and Michael Green, journalist Hanna Rosin, and environmental activist Paul Gilding.

The force behind scientific progress is the simple act of asking questions. This episode, TED speakers explore how a deeper and more humble style of inquiry may help achieve the next big breakthrough. Guests include educator Michael Stevens, professor and science historian Naomi Oreskes, surgeon Kevin Jones, former college president Liz Coleman, and author Eric Haseltine. (Original broadcast date: February 24, 2017.)

Moments of crisis can upend our lives, but can also help define them. This episode, TED speakers explore how a quick, compassionate or unexpected response can turn crisis into opportunity. (Original broadcast date: April 1, 2016.)