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Discover the hidden truths of Medical Research as Dr. Michael Koren from ENCORE Research Group illuminates the intricate dance of clinical trials, delivering a masterclass on personalized patient care and informed decision-making in this week's MedEvidence Monday Minute. As I, Kevin Geddings, guide the conversation, we reveal the critical parallels between sports strategy and the leadership required to manage high-pressure situations in healthcare. This episode promises to unravel the complexity behind the scenes, offering you a rare peek into the meticulous world that shapes the medicines and treatments of tomorrow.

We're peeling back the curtain on clinical trials with stories straight from the front lines, as Dr. Koren recounts his early morning strategy for tackling potential side effects in a patient's trial participation, showcasing the expertise and dedication that is a signature of Encore Research Group Dr. Richard Myers and Dr. Valerie Hayes, our seasoned medical director and expert site manager respectively, also earn the spotlight for their roles in steering these medical explorations. Together, we navigate the nuanced layers of patient care, strategy, and innovation that define the future of medicine. Tune in and be part of a conversation that's as enlightening as it is essential for anyone interested in the cutting edge of healthcare.

Recording Date: January 8, 2024

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Embark on an enlightening exploration of systemic lupus erythematosus (SLE) with the insightful Dr. Shah on MedEvidence. We delve deep into the perplexing world of lupus, shedding light on its signature symptoms like the striking malar rash, while clarifying common misconceptions to foster a better understanding of this enigmatic condition. Beyond its cutaneous manifestations, we discuss how lupus can affect multiple organs and the significance of genetic predisposition, offering a comprehensive look at why this disease remains a formidable challenge in the medical community.

Navigating the lupus diagnosis and management maze can be as complex as the disease itself. Join us as we dissect early warning signs, from the elusive fatigue and Raynaud's phenomenon to more overt cues that may often be mistaken for less serious health issues. With Dr. Shah's guidance, we reveal the intricacies of the diagnostic process, emphasizing the necessity of a multifaceted treatment strategy. We don't hold back on discussing the potential complications of lupus, particularly when it comes to pregnancy, underscoring the critical nature of vigilant disease management.

As we move towards a future filled with medical advancements, we share a message of hope for those living with lupus. We cover the gamut of treatment options, from the tried-and-true hydroxychloroquine to the breakthrough potential of JAK inhibitors, and offer practical tips for day-to-day living with lupus. Our conversation ultimately culminates with an invitation for listeners to join forces in the ongoing quest for autoimmune disease research breakthroughs, empowering you to become an active participant in the journey towards a brighter, healthier future.

Lupus Snapshot:

📸Understanding Lupus
📸Diagnosing and Managing Lupus
📸Therapies and Tips for Lupus
📸Jack Inhibitors for Autoimmune Diseases 
📸Getting Involved in the Future

Recording Date: November 29, 2023

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Unlock the deeper meaning behind the well-worn New Year's wish of health, happiness, and prosperity with Dr. Michael Koren, whose passion for medical research offers a fresh take on these timeless hopes. As a seasoned cardiologist and research scientist, Dr. Koren joins us to dissect this classic greeting, revealing the interconnectedness of these ideals within the realm of healthcare and personal fulfillment. Get set to transform your understanding of what it truly means to extend these well-wishes as we explore the tangible ways they manifest in our lives.

During our conversation, Dr. Koren unravels how prosperity goes beyond mere wealth, touching on the rewards of clinical research participation and the profound impact that contributing to medical advancements can have on individuals and communities. He explains the dual nature of health – preventing illness and optimizing the management of chronic conditions – and how his organization, ENCORE Research Group, propels both. Most poignant is the exploration of happiness, where Dr. Koren shares the insight that true contentment comes from achievement and contribution, not just from what we possess. This episode is a heartfelt reminder of the power behind our New Year's aspirations and an invitation to pursue them with intention in all aspects of our lives.

Recording Date: January 2, 2023

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Are myths about vaccines and their DNA-altering capabilities clouding your judgement? Let us arm you with facts as we journey through the complexities of viruses and the marvels of modern immunizations. Together, we’ll navigate the intricate relationship between these microscopic invaders and the defense mechanisms of our bodies. Expect a thorough examination of how vaccines employ fragments of a virus's spike protein to elicit an immune response, a giant leap from the days of using inactivated viruses. Our discourse aims to dismantle doubts and empower you with the confidence to champion the cause of vaccine safety and efficacy in your community.

Our immune system is an unsung hero, and in this episode, we give it the spotlight it deserves. We'll explore the timeline of antibody production post-exposure, revealing the nuanced roles of IgM and IgG antibodies and the lasting protection they offer. We'll also discuss the valiant T cells and B cells, the architects of cellular immunity. By understanding how our bodies recruit these cells to fend off infections, you'll gain a newfound appreciation for the science behind the structure of antibodies and their vital role in our well-being.

Taking a step back in history, we delve into the contributions of diverse communities in the realm of vaccines—an homage to the pioneers who laid the groundwork for today's medical miracles. But it doesn't stop there; we also gaze into the crystal ball of vaccine technology, discussing the groundbreaking potential of combined flu and COVID-19 vaccines and the promising advancements that could see vaccine development times slashed to mere months. This episode is not just a celebration of medical achievements; it's a testament to the collective power of communities, like the 2,000 Northeast Florida participants in vaccine trials, whose efforts fuel the relentless pursuit of health innovation. Join us for a riveting tale of human ingenuity and resilience in the face of disease.

MedEvidence Checkup:
✅Understanding Vaccines and Viruses
✅Understanding the Immune System and Vaccines
✅The History and Production of Vaccines
✅Understanding the Process of RNA Vaccine
✅Future of Vaccines and Flu-Covid Vaccine


Recording Date: October 27, 2023

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Prepare to have your perception of cannabis transformed! In our final episode of Two Docs Talk Cannabis, Dr. Michael Koren and Dr. Erich Schramm you on an insightful journey into the complex world of cannabis research. They break down the walls of misunderstanding surrounding this Schedule I drug, shedding light on its potential reclassification, and introducing you to the game-changing pharmaceutical products derived from it. Join the Cannabis Conversations to explore this controversial field and its promising future.

Are you aware of the numerous components of marijuana and their effects? It's not as straightforward as traditional drugs, and that's where Dr. Schramm and Dr. Koren explore the concept known as the entourage effect, giving you a better understanding of the intricacies of this dynamic plant, debate the importance of the endocannabinoid system and its place within medical education. Moreover, they highlight the ever-increasing potency of THC content in modern marijuana, a crucial factor often overlooked. Join us as we demystify cannabis, reflecting on its past, analyzing its present, and predicting its future.

Listen to the entire series:

Part 1: Cannabis 101 - Released November 27, 2023

•    CBD vs. THC
•    Delta-8 and Delta-9
•    Terpenoids and Flavonoids
•    Sativa, Indica and Hybrids
•    Endocannabinoid System

Part 2: Cannabis Conversations - Types of Patients Treated - Released December 6, 2023

•    Common Conditions Treated
•    Case Studies

Part 3: Step by Step to Cannabis Certification - Released December 13, 2023

•    How does a patient get certified
•    Certification Process
•    Driving and Traveling with Cannabis
•    Health and Healing Benefits

Part 4: Rescheduling & Research of Cannabis - Released December 20, 2023

•    Schedule 1 vs 2 vs 3
•    Financial Implications
•    Research Implications

Recording Date: November 16, 2023

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Have you ever felt the frustration of a self-checkout area at a grocery store and then noticed the same in your interaction with your medical provider? With the retail industry's lessons in our minds, we turn the spotlight on the healthcare service in our conversation with Dr. Michael Koren. We navigate through the impact of service in our health care system - or the lack of it - and the dangers of relying on Dr. Google, drawing from real-life anecdotes shared by Dr. Koren. We also broach the topic of clinical trials, unearthing how service is a fundamental layer in this realm.

As we move closer to the holiday season, we continue engaging with Dr. Koren on the future of medicine. We probe into the role of technology in healthcare, the uphill battle of implementing evidence-based practices, and the vital importance of staying abreast with medical research. And as we bid adieu to this enlightening conversation, Dr. Koren sends us warm holiday wishes and you, our valued listeners. Join us for this enlightening episode and keep your ears primed for more stimulating discussions in the coming year!

Recording Date: December 18, 2023

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Craving a dose of both music trivia and medical knowledge? Get ready to satiate your appetite on the MedEvidence Monday Minute radio show. Our guest, Dr. Michael Koren, an expert in medical research, not only serves up some surprising facts about the Monkees and their unlikely touring partner, Jimi Hendrix, but also offers an in-depth discussion on leading medical research. 

Today's spotlight is on heart health, Dr. Koren skillfully breaks down the complex medical jargon associated with congestive heart failure, explaining what it means to be 'congestive' and the implications for your heart when it falls short of your body's requirements. He discusses the different types of congestive heart failure, including heart failure with reduced ejection fraction (HEF-REF) and heart failure with preserved ejection fraction (HEF-PEF). It's not all medical jargon though, as our conversation effortlessly weaves in references to rock and roll, making for a uniquely entertaining and educational experience. Plug in for an exciting blend of laughter, learning, and music!

Be a part of advancing science by participating in clinical research.

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Ever wondered about the untapped potential of medical cannabis? Join us, as we sit down with cannabis specialist, Dr. Erich Schramm, and unwrap the therapeutic powers of this often misunderstood plant. Imagine finding relief from chronic pain or anxiety through carefully tailored cannabis treatments, such as edibles and tinctures. Understanding your sensitivity to THC is crucial to avoiding potential side effects like heart palpitations and anxiety. Take heart, though, because quality CBD products can counteract these effects. Our conversation with Dr. Schramm is a beacon for those in search of alternative treatments, shedding light on the medicinal benefits of cannabis.

We take you inside Dr. Schramm's office to illustrate what a patient's experience looks like. Immerse yourself in this enriching dialogue and discover more about the healing wonders of medical cannabis.

Listen to the entire series:

Part 1: Cannabis 101 - Released November 27, 2023

•    CBD vs. THC
•    Delta-8 and Delta-9
•    Terpenoids and Flavonoids
•    Sativa, Indica and Hybrids
•    Endocannabinoid System

Part 2: Cannabis Conversations - Types of Patients Treated - Released December 6, 2023

•    Common Conditions Treated
•    Case Studies

Part 3: Step by Step to Cannabis Certification - Released December 13, 2023

•    How does a patient get certified
•    Certification Process
•    Driving and Traveling with Cannabis
•    Health and Healing Benefits

Part 4: Rescheduling & Research of Cannabis - Released December 20, 2023

•    Schedule 1 vs 2 vs 3
•    Financial Implications
•    Research Implications

Recording Date: November 16, 2023

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What if a highly structured, disciplined approach could revolutionize your health? What if it could be as simple as incorporating two hours of exercise per week into your routine? This week's MedEvidence Monday Minute, Dr. Michael Koren shares how scheduling and structure can be life-changing in both healthcare and daily life. He sheds light on the transformative power of exercise, and how incorporating it into your daily routine can do a world of good.

Dr. Koren doesn't stop at personal habits, he takes us on a journey into the world of clinical trials, showing us how a structured, scheduled approach can lead to better results and commitment from participants. He emphasizes the importance of the 'apples to apples' comparison for reliable results in these trials, ensuring the same protocols are followed, no matter where the study takes place. He also gives us a peek into the challenges of navigating the increasingly complex realm of healthcare information in our digital age. Join the conversation and discover how structure can lead to a healthier, more informed life.

Recording Date: December 4, 2023

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Ready to unravel the complexities of cannabis and its myriad chemical compounds? Prepare to be enlightened as we invite family physician and researcher Dr. Erich Schramm to share his insights on the medicinal use of this fascinating plant. With years of experience under his belt, Dr. Schramm dives into the differences between cannabidiol (CBD) and tetrahydrocannabinoid (THC), as well as the intoxicating potential of Delta 8 and Delta 9 components. He also provides valuable context on how the 2014 Farm Bill influenced the rise of the CBD industry.

Dr. Schramm further explores the accessibility of Delta 8 over-the-counter and the reasons why certain products necessitate a medical marijuana solution. Touched upon, too, are the integral roles terpenes, terpenoids, and flavonoids play in the composition of the plant. This illuminating episode promises to expand your understanding of cannabis, with Dr. Schramm's wealth of knowledge giving you the facts and debunking the myths along the way. Tune in the following weeks as new episodes are released.

You will learn:

• Cannabis 101 Released November 27, 2023
  • CBD vs. THC
  • Delta-8 and Delta-9
  • Terpenoids and Flavonoids
  • Sativa, Indica and Hybrids
  • Endocannabinoid System
• Cannabis Conversations Released December 6, 2023
  • Common Conditions Treated
  • Cast Studies
• Practicalities: Step by Step to Cannabis Released December 13, 2023
  • How does a patient get certified
  • Certification Process
  • Driving and Traveling with Cannabis
  • Health and Healing Benefits
• Rescheduling & Research of Cannabis Released December 20, 2023
  • Schedule 1 vs 2 vs 3
  • Financial Implications
  • Research Implications

Recording Date: November 16, 2023

Be a part of advancing science by participating in clinical research.

Have a question for Dr. Koren? Email him at [email protected]

Listen on Spotify
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Share with a friend. Rate, Review, and Subscribe to the MedEvidence! podcast to be notified when new episodes are released.

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