In this podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss a formulation of melatonin that has been licensed in the UK for the management of jet lag. The editors review the evidence for its effectiveness in reducing symptoms of jet lag and consider whether it should be available from the National Health Service. Read the article here: http://dx.doi.org/10.1136/dtb.2019.000074.