Urgent manhunt for Louisiana escaped inmates; Devastating tornado hits St. Louis; Commuter chaos as NJ Transit engineers go on strike; and more on tonight’s broadcast.

Biden diagnosed with ‘aggressive’ form of prostate cancer; 2 dead, more than a dozen injured after Mexican navy ship crashes into Brooklyn Bridge; FBI calls California fertility clinic bombing an ‘act of terrorism’; and more on tonight’s broadcast.

Urgent manhunt for Louisiana escaped inmates; Devastating tornado hits St. Louis; Commuter chaos as NJ Transit engineers go on strike; and more on tonight’s broadcast.

Justices hear arguments in birthright citizenship case; Cassie Ventura cross-examined in Sean ‘Diddy’ Combs’s trial; Air traffic control outage in critical Denver airport hub; and more on tonight’s broadcast.

Cassie Ventura testifies about physical abuse and rape at Diddy trial; Trump in Qatar on high-stakes Mideast trip; Dangerous early heat wave scorches Texas; and more on tonight’s broadcast.

Sean ‘Diddy’ Combs’ ex-girlfriend Cassie Ventura gives bombshell testimony; Menendez brothers resentenced to 50 years to life with parole; Trump kicks off high-stakes mideast trip in Saudi Arabia; and more on tonight’s broadcast.

Stocks surge after U.S. and China announce pause on most tariffs; Lester Holt speaks with Pope Leo; U.S. hostage Edan Alexander released; and more on tonight’s broadcast.

Hamas says it will release last living American hostage in Gaza; New air traffic control outages in Newark and Atlanta; New questions on White House's deal with China; and more on tonight’s broadcast.

Pope Leo XIV makes surprise appearances on Saturday; 4.1 earthquake rocks southern states; U.S. China negotiators meet in Switzerland for trade talks; and more on tonight’s broadcast.