Radio host Delilah Rene Luke has been on the air for decades. Her show “Delilah” has racked up 8-10 million weekly listeners across 160 radio stations, making her the most listened-to woman in the history of American radio. When she’s not on the air, Delilah is busy: She’s the mother of some 18 children, most of whom she adopted, with serious health conditions. After a break to grieve the loss of one of those sons, Zach, she’s back on the air. She joins Yas this Christmas Eve to talk about where her show began, how she connects with people through music, and coping with challenges.

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The FDA has approved a pill version of the GLP-1 weight loss drug Wegovy from Novo Nordisk. The Department of Health and Human Services could be setting a new vaccine schedule. And ACA subsidies are set to expire at the end of the year. We speak with NBC News Medical Contributor Dr. Natalie Azar about the new developments and why the rising cost of health care is creating anxiety among nearly half of U.S. adults. Plus: Ahead of the holidays, we have weather, travel and shopping updates for your last-minute trips

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Lawmakers say they’re taking action after the Justice Department failed to release all the docs related to Jeffrey Epstein by Friday’s deadline – and much was blacked out in what was released. Then, Epstein survivor Sharlene Rochard explains what the redactions and lack of transparency mean for those still seeking justice and accountability. Plus, NBC News is reporting exclusively on a growing rift between Secretary of State Marco Rubio and special envoy Steve Witkoff over Russia-Ukraine peace talk strategy. NBC News investigative reporter Dan De Luce joins us to talk about what that divide could mean for the path forward.

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A five-day search for the Brown University shooting suspect has ended with 48-year-old Claudio Manuel Neves Valente found dead in a New Hampshire storage facility from an apparent self-inflicted gunshot wound. Authorities say the suspect is also connected to the fatal shooting of an MIT professor this week – a connection they made after a Reddit user posted a crucial clue. NBC News National Law Enforcement and Intelligence Correspondent Tom Winter explains how it all went down. And your doom-scrolling is safe: After years of uncertainty, Chinese parent company ByteDance has signed a binding deal to create a joint U.S. venture for TikTok, brokered by the Trump administration. The U.S. version will be majority-owned by American investors, effectively saving the app from a ban. NBC News Now Anchor and TikTok aficionado Savannah Sellers breaks down what this means for users. Plus: The DOJ has started releasing thousands of documents from the Epstein Files.

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Nearly a year into his second term, President Donald Trump took to prime time from the White House to make his case to the country. NBC News Senior White House Correspondent Garrett Haake joins us to separate fact from fiction and unpack what the speech says about the political moment, as the president’s approval ratings continue to dip. Then, social media companies are under growing pressure over their impact on teens. NBC News is reporting exclusively that the families of two boys who died by suicide have sued Meta, alleging the company ignored the dangers of “sextortion” on Instagram. NBC News Tech Reporter David Ingram joins us with the details and what it could mean for Big Tech.

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Nick Reiner, son of acclaimed director Rob Reiner and Michele Singer Reiner, was arraigned in Los Angeles Superior Court. He’s charged with two counts of first-degree murder in his parent’s deaths. NBC News correspondent Gadi Schwartz has the latest on the Hollywood tragedy. And President Trump is expected to sign an executive order this week fast-tracking the reclassification of marijuana. NBC News correspondent Julie Tsirkin, who covers the White House, has more on a move that would mark a major shift in U.S. drug policy.

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The jobs report from October and November that was on ice because of the government shutdown shows major losses in federal jobs in October, but a small upward tick in November. The Trump administration is touting private-sector wage growth. NBC News Senior Business Correspondent Christine Romans joins us to make sense of the numbers. Then, Senior Investigative Producer Dan Slepian brings us an NBC investigation into the fallout from a conviction connected to shaken baby syndrome, and why new science is not leading to exonerations. Plus: Nick Reiner charged with two counts of murder in the deaths of his parents, updates on the shootings at Bondi Beach, and why one couple got married for the first time on their 50th anniversary.

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On the pod today, three tragedies that ended in multiple lives lost over the weekend. Our national law enforcement and intelligence correspondent Tom Winter gives us the latest on the manhunt in Rhode Island, in the search for the person who opened fire at Brown University, killing two students and wounding nine people, and the mass shooting by a father and son on Bondi Beach in Australia that left 15 people dead and more than two dozen wounded. Then, national correspondent Morgan Chesky reports from Brentwood, California, where noted Hollywood actor and filmmaker Rob Reiner and his wife, Michele Singer Reiner, were found dead in their home Sunday. Police have taken their son Nick Reiner into custody on suspicion of murder. Our entertainment correspondent Chloe Melas has more on Rob Reiner's legacy.

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On today’s show: After senators failed to pass two partisan health care bills, lawmakers in the House are trying to get to a bipartisan deal before the enhanced Affordable Care Act subsidies expire at the end of the year, leaving millions of Americans facing soaring insurance premiums. Plus: House Democrats have released a new set of pictures from the Epstein files, part of a 95,000 document trove. NBC’s Ryan Nobles reports from Washington. Then, a vaccine for triple-negative breast cancer shows promise in early clinical trials. Dr. Kavita Patel has the details. And: is Timothée Chalamet a secret rapper?

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The U.S. has seized an oil tanker off the coast of Venezuela, a move President Donald Trump is calling “the largest one ever seized.” The White House says the ship is a “sanctioned shadow” vessel tied to the Iranian military and that the administration plans to take possession of the oil on board. Press secretary Karoline Leavitt said the tanker is moving through a federal forfeiture process, which includes interviewing the crew and collecting evidence. NBC News senior national security correspondent Courtney Kube joins host Yasmin Vossoughian to break it down. Meanwhile, artificial intelligence is everywhere, and Disney is jumping in. Time has named the “Architects of AI” its 2025 Person of the Year, and Disney just struck a deal with OpenAI to bring its beloved characters into the Sora social video app, alongside a billion-dollar investment to supercharge the technology. NBC News reporter Jared Perlo joins the pod.

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