Jean Nachega is an associate professor of infectious diseases and microbiology and of epidemiology at the University of Pittsburgh School of Public Health and a professor of medicine at Stellenbosch University. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. J.B. Nachega and Others. PEPFAR at 20 — A Game-Changing Impact on HIV in Africa. N Engl J Med 2023;389:1-4.