New Alzheimer’s Drug Reduces Cognitive Decline, Say Biotech Firms

This week, the biotech firms Biogen and Eisai released preliminary data from the clinical trials for their new Alzheimer’s drug, lecanemab. The companies said that the drug slowed cognitive decline by 27% in patients treated with the intravenous medication. It’s likely the drug will get the FDA’s approval by the end of the year.

This all comes after the recent controversy surrounding Biogen’s last Alzheimer’s drug Aduhelm. Medicare recently announced that they will not cover that drug and others like it, unless patients are enrolled in a clinical trial.

Guest host John Dankosky talks with science journalist Roxanne Khamsi about this and other top science news of the week including a diamond that hints that Earth’s mantle contains water, brainy birds, and hearing aids made of false teeth.

The People’s Republic of Bangladesh is one of the most densely populated countries on Earth, with a population of 165 million people living in an area a bit smaller than the state of Iowa. To feed all those people, farmers in Bangladesh work year-round: Instead of just growing crops during the rainy monsoon season, they grow a second or even third crop during the dry season—using groundwater to irrigate, and creating a more food-secure region.

Research published in the journal Science this month found something amazing about all that groundwater. By pumping water for crops in the dry season, Bangladeshi farmers were leaving space in the aquifers to recharge during the rainy monsoon season. And this space allowed the aquifers to recapture more than 20 trillion gallons of water, or twice the capacity of China’s massive Three Gorges Dam, over the last 30 years.

The researchers call this the Bengal Water Machine, evidence for a similar concept that was first proposed nearly 50 years ago called the Ganges Water Machine.

Guest host John Dankosky talks to lead author Mohammad Shamsudduha and International Water Management Institute researcher Aditi Mukherji about how this groundwater pumping benefits farmers, and the need for more data as climate change continues.

Jim Metzner is one of the pioneers of science radio—he’s been making field recordings and sharing them with audiences for more than 40 years. He hosted shows such as “Sounds of Science” in the 1980s, which later grew into “Pulse of the Planet,” a radio show about “the sound of life on Earth.”

Over the decades, Metzner has created an incredible time capsule of soundscapes, and now, his entire collection is going to the Library of Congress.

John Dankosky talks with Metzner about what he’s learned about the natural world from endless hours of recordings and what we can all learn from listening. Plus, they’ll discuss some of his favorite recordings. To hear the best audio quality, it might be a good idea to use headphones if you can.

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