Oral antiviral agents may be a promising tool to reduce hospitalizations and death in patients with COVID-19. New data and research about these therapies are emerging. In this episode, experts discuss oral antiviral agents for COVID-19 and the uses of these medications. (Originally recorded January 27, 2022) Moderator: Alice Gallo de Moraes, MD. Panelists: Steven Gordon, MD; Catherine M. Berjohn, CDR, MC, USN; and Prashant Malhotra, MBBS, MD. For more tools to help in the fight against COVID-19, visit CHEST’s COVID-19 Resource Center at chestnet.org/COVID19.