This podcast highlights original research appearing in the May 2013 issue of Otolaryngology - Head and Neck Surgery, the official journal of the American Academy of Otolaryngology - Head and Neck Surgery (AAO-HNS) Foundation. Editor in chief Richard Rosenfeld is joined in by lead author Stephanie Shintani Smith and associate editor John H. Krouse in discussing factors related to variations in antibiotic prescribing for acute rhinosinusitis in United States ambulatory care settings.