In Part 2 of this discussion of the 2018 ATS/ERS/JRS/ALAT Guideline, we discuss the approach to invasive procedures in suspected IPF and unanswered questions/directions of future research in IPF.

Dr. Nitin Seam moderates a discussion of the 2018 ATS/ERS/JRS/ALAT Guideline with authors Ganesh Raghu and Kevin Wilson. Part 1 discusses the history, how the guideline questions were formulated and the non-invasive workup.

Dr. Fleetham is joined by Drs. Julia Chapman and Sanjay Patel to discuss their respective article and editorial on alternatives to CPAP and the role Armodafinil could possibly play.

John Fleetham is joined by Chris Turnbull, lead author of the paper “Effect of Supplemental Oxygen on Blood Pressure in Obstructive Sleep Apnea (SOX): A Randomised, CPAP Withdrawal Trial”.

Drs. Lorenzo Berra and Mark Gladwin join Nitin Seam to discuss an interesting trial looking at the effect of inhaled nitric oxide on hemolysis and renal failure post cardiac surgery

Dr. Trish Kritek is joined by Drs. Luciano Gattinoni and Taylor Thompson to discuss Gattinoni’s article on the topic.

Drs. Gerard Criner and Gaetan Deslee join Nitin Seam to discuss the results of the multi-center LIBERATE trial, the first endobronchial valve study to follow patients for 12 months.

Dr. Fleetham discusses phenotyping using polysomnography in patients with COPD with Drs. Scott Sands and David Rappoport

Dr. Wedzicha joins Nitin Seam to give her perspective on 3 important papers from the conference issue of the blue journal and to discuss some current and future articles of interest.

Drs. Atul Malhotra and Safwan Badr join Dr. Fleetham to discuss the article “Research priorities in pathophysiology for sleep-disordered breathing (SDB)in patients with chronic obstructive pulmonary disease (COPD)”