AstraZeneca’s good vaccine news is tempered by federal health officials voicing concerns about the company’s data. CNBC’s Meg Tirrell digests the news and considers the blow’s impact to the vaccination timeline in the U.S. A year after U.S. stocks plummeted on fears of the coronavirus pandemic, markets have bounced back, in what Mike Santoli calls their best year since the 1930s. CEOs are facing tough decisions as they plan office reopenings; KPMG CEO Paul Knopp shares results from his survey of 140 other U.S. CEOs, addressing C-suite concerns for safety, employee demands for flexibility, and workplace vaccination disclosures post-pandemic. Plus, March Madness has spelled good fortune for the newest addition to the S&P 500: Penn National Gaming. CEO Jay Snowden discusses bets, brackets, and expanding American gambling.  

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