Blood Podcast

Phosphoseryl-tRNA kinase inhibition in acute myeloid leukemia (AML), APOE gene variants and post-hematopoietic stem cell transplant outcomes in AML, and the role of chronic inflammation in sickle cell cardiomyopathy

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In this week's episode we’ll learn more about how phosphoseryl-tRNA kinase inhibition promotes cell death in acute myeloid leukemia, or AML; APOE gene variants and their association with post-hematopoietic stem cell transplant outcomes in AML; and pathways by which chronic inflammation and oxidative stress may lead to cardiomyopathy in patients with sickle cell disease.

Featured Articles:

  • PSTK inhibition activates cGAS-STING, precipitating ferroptotic cell death in leukemic stem cells 
  • Common Hereditary Variants of the APOE Gene and Posttransplant Outcome in Acute Myeloid Leukemia 
  • 17R-Resolvin D1 Protects Against Sickle Cell Related Inflammatory Cardiomyopathy in Humanized Mice 
...more
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Blood PodcastBy American Society of Hematology
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