Blood Podcast

Pirtobrutinib plus venetoclax with or without rituximab in relapsed/refractory CLL; murine models of erythroid 5ALA synthesis disorders; targeting PKCa in diabetes and hemochromatosis


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In this week's episode we’ll discuss the safety and efficacy of pirtobrutinib with or without rituximab in relapsed/refractory CLL; learn more about erythroid 5ALA synthesis disorders and their conditional synthetic lethal dependency on pyridoxine; and discuss how targeting PKC alpha alleviates iron overload in diabetes and hemochromatosis through the inhibition of ferroportin.

Featured Articles:

  • Fixed-duration pirtobrutinib plus venetoclax with or without rituximab in relapsed/refractory CLL: Phase 1b BRUIN trial
  • Murine models of erythroid 5ALA synthesis disorders and their conditional synthetic lethal dependency on pyridoxine
  • Targeting PKCα alleviates iron overload in diabetes and hemochromatosis through the inhibition of ferroportin


...more
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Blood PodcastBy American Society of Hematology

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