In this episode, Dr. Jeff Dikis and Dr. Leland Jaffe discuss the management of infections in patients, specifically focusing on antibiotic treatment. They talk about the challenges of antibiotic management, the importance of following guidelines, and the role of infectious disease doctors. They also discuss the future of antibiotic treatment and the emergence of antibiotic-resistant bacteria. The conversation highlights the need for collaboration between different specialties, such as vascular and infectious disease, to ensure effective treatment. They cover topics such as the use of antibiotics, the importance of culture and sensitivity testing, and the role of vancomycin powder in reducing the risk of surgical site infections. Overall, the conversation provides valuable insights into the management of infections in foot and ankle surgery.