"Off Message" presents the second episode of the new season of POLITICO's podcast "Global Translations": 

Once there is a working Covid vaccine, manufacturers across the globe will need to scale up production to produce billions of doses — meaning billions of pharmaceutical-grade glass vials, rubber stoppers, packaging and storage and refrigeration. In a special airing of POLITICO's Global Translations podcast, hosts Luiza Savage and Ryan Heath look at the challenges of making enough vaccines for the world.

Luiza Savage is the host of "Global Translations"
Ryan Heath is a host of "Global Translations"
Annie Rees is a producer for POLITICO Audio
Kara Tabor is a producer for POLITICO Audio
Jenny Ament is the senior producer for POLITICO Audio
Irene Noguchi is the executive producer of POLITICO Audio

Sarah Owermohle is a POLITICO health reporter covering vaccines. 
Dr. Anthony Fauci is the director of the National Institute of Allergy and Infectious Diseases.
Jim Robinson is a former MERCK executive (manufacturing lead for ebola project); currently with CEPI (Coalition for Epidemic Preparedness Innovations).
Dan Diamond is a POLITICO health care reporter and the host of the "Pulse Check" podcast and newsletter. 

Check out and subscribe to POLITICO's Global Translations, POLITICO Pulse, and Global Pulse newsletters. Read Luiza Savage's article on why nationalism is the next big challenge for Covid-19 vaccines. 

Global Translations newsletter: https://www.politico.com/newsletters/global-translations
POLITICO Pulse newsletter: https://www.politico.com/politicopulse/
Global Pulse newsletter: https://www.politico.com/newsletters/global-pulse
POLITICO article: "The next vaccine challenge: Nationalism": https://www.politico.com/news/2020/10/28/covid-vaccine-challenge-nationalism-433023

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"POLITICO's Off Message" brings you a special episode of POLITICO's new podcast series "Global Translations." 

From closed factories to closed borders, the Covid-19 pandemic exposed the fragility of our systems, creating a period of scarcity where demand skyrocketed — from freezers to PPE — and we couldn't supply items fast enough. In this episode of "Global Translations", POLITICO hosts Luiza Savage and Ryan Heath take a deep dive with experts into global supply chains and what "decoupling" and "reshoring" are all about when it comes to America’s reliance on China and the rest of the world.

Luiza Savage is the host of "Global Translations". 
Ryan Heath is a host of "Global Translations".
Annie Rees is a producer for POLITICO Audio.
Kara Tabor is a producer for POLITICO Audio.
Jenny Ament is the senior producer for POLITICO Audio.
Irene Noguchi is the executive producer of POLITICO Audio.

Adegoke Oke is a professor of supply chain management at Arizona State University.
Tom Duesterberg is a senior fellow at Hudson Institute. He is an expert on trade and foreign policy. 
David Wertime is POLITICO's editorial director for China and author of the China Watcher newsletter.

Check out and subscribe to POLITICO's Global Translations and China Watcher newsletters, and Luiza Savage's in-depth piece on how the pandemic is forging a new consensus on globalization.

Global Translations: https://www.politico.com/newsletters/global-translations China Watcher: https://www.politico.com/newsletters/politico-china-watcher Supply chain tug-of-war article: https://www.politico.com/news/2020/10/21/pandemic-forging-new-consensus-globalization-430605

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Rahm Emanuel — former Chicago mayor and former chief of staff to President Barack Obama — talks to POLITICO founding editor John Harris about his new book, "The Nation City: Why Mayors Are Now Running the World," his "toy phone" in Bill Clinton's White House and his thoughts on the 2020 field.

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We're bringing you an episode of POLITICO's Global Translations, a show about big global problems that will take a certain amount of creativity to solve. 

Driven by a public clamoring for action and pressure from corporate CEOs, lawmakers are noting an evolution in attitudes toward climate action among some of their Republican colleagues – a subtle but significant shift in tone that could pave the way for modest legislation this year. Guests include:Rep. Earl Blumenauer (D-OR)Rep. Francis Rooney (R-FL)Sen. Chris Coons (D-DE)Catherine McKenna, Canada’s first foreign minister for climate and the environmentDan Byers, U.S. Chamber of CommerceIf you like the episode, check out the show wherever you listen. 

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To get the inside view from the only people in the world who know what it’s like to run in a primary field so large -- and do so in the shadow of Donald Trump -- we invited the strategists for four of the top GOP primary campaigns of 2016 into a Washington cigar bar, a literal smoke-filled room, to talk shop. Which Democratic candidate has the most raw political talent? What weaknesses of Donald Trump's would they exploit in 2020? And why is everybody still so ticked off about the Virginia primary?

Guests Danny Diaz (from the Bush campaign), Beth Hansen (Kasich), Jeff Roe (Cruz), and Terry Sullivan (Rubio).

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Kirsten Gillibrand is a U.S. Senator with a soaring national profile, but her presidential campaign has yet to take flight. She’s even at risk of failing to have enough donors to make the debate stage under DNC rules, leading her to ask people for just a dollar, to boost her numbers. But that’s not what bothers her most about running for president. 

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In a crowded field of Democratic presidential contenders, former Colorado Gov. John Hickenlooper makes an impression on voters as a genuine candidate, even if he's a bit quirky. He colors outside the lines of the political conventions -- a geologist by training, a brewer and restauranteur by profession, and a politician only later in life. 

In this episode, he talks about his temper as a child, his pragmatic approach to politics, and how he's managed to succeed in a people-driven business despite a condition commonly known as face blindness, a condition that keeps him from recognizing familiar faces. 

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For our post-midterms edition of Off Message, we talked to Corry Bliss and Charlie Kelly, the two men who led the largest House campaign organizations in 2018. This election, Bliss led the Republican-aligned Congressional Leadership Fund, and Kelly led its Democratic counterpart, the House Majority PAC. They talk about what went on behind the scenes, their biggest regrets of 2018, and where things go from here.

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The strategist behind Obama's presidential campaigns gives his midterms predictions, shares his lightning-round thoughts on 2020 candidates and tells Tim whether he thinks any politician can recapture the Obama magic.

David Axelrod doesn’t like the path the country—or the Democratic Party—is on. 

The chief strategist who steered Barack Obama’s winning White House campaigns worries that President Trump has laid a trap—and that his party is walking right into it. “Escalation breeds escalation,” Axelrod said in an interview for POLITICO’s Off Message podcast. “And within the Democratic Party, I think there is a big debate about how to deal with Trump because he has no boundaries. He’s willing to do anything and say anything to promote his interests. It’s a values-free politics; it’s an amoral politics. And so, there is this body of thought that you have to fight fire with fire and so on. But I worry that we’ll all be consumed in the conflagration.” 

Stressing that “civility actually is a really important element of politics,” Axelrod criticized Hillary Clinton and former Attorney General Eric Holder for recent comments they’ve made, and described the backlash he has faced for urging Democrats to avoid confrontation. The best way to defeat Trump, Axelrod argued, is by nominating someone who can appeal to an exhausted electorate. 

“I don’t think people will be looking for a Democratic version of Trump,” he said. “I don’t think they’ll be looking for people who can go jibe for jibe and low blow for low blow. I think people are going to be looking for someone who can pull this country out of this hothouse that we’re in.” 

At his offices in Chicago, where he directs the University of Chicago’s Institute of Politics, we discussed Axelrod’s predictions for the midterm elections, the risk of overreach with a new House majority, and the strengths and vulnerabilities of the top-tier 2020 Democratic hopefuls. 

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When Chip Roy was a top staffer for Ted Cruz, he was an architect of the Texas senator’s strategy to shut down the government over Obamacare.

Now, in all likelihood, he’s heading for Congress with a House seat of his own, and top Republicans worry he’s going to make Cruz look like a squishy moderate.

Roy is ready to play hardball with GOP leaders in Congress. He has pledged to support House Freedom Caucus founding chairman Jim Jordan for speaker, and is expected to quickly establish himself as one of the House GOP’s most outspoken and combative members.

As with so many conservatives, however, Roy is treading lightly when it comes to Donald Trump. Once a fierce critic—described by friends as a committed “Never Trump” advocate in 2016, when he was working in support of Cruz’s presidential campaign—the congressional hopeful now talks fondly of the president, praising his assault on “the swamp” and sharing his concern about a “deep state” acting as a shadow government.

And while most Republicans campaigning for Congress this November are touting the accomplishments of President Trump and his GOP majorities: tax reform, regulatory relief and a soaring number of federal judicial appointments. In the deep-red 21st congressional district of Texas, Chip Roy is running on a different message: Republicans haven’t done nearly enough.

“If there is a thousand miles to go, we’ve gone maybe 50 miles,” Roy tells POLITICO’S “Off Message” podcast. “So now, we’ve got to focus on the things that the people really want to see done. We’ve got to have healthcare freedom, we’ve got to balance the budget and we’ve got to secure the border.”

POLITICO's "Off Message" podcast is hosted by Tim Alberta, produced by Zack Stanton and executive produced by Dave Shaw. Intro/outro music by Podington Bear.

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