This piece focuses upon the unique 'Collaborative Clinical Trials in Anaesthesia biennial conference', of which this was the fifth, organised in Prato, Italy, by Monash University.

TopMedTalk was given the chance to listen in on this cutting edge gathering of trialists, academics and practitioners as it happened. We take a deeper dive on the history behind this very special meeting, how it works and special moments from the meeting.

Learn how some of the big trials gather pace and how major studies get established.

The ANZCA Clinical Trials Network is here: http://www.anzca.edu.au/ctn

More detail on the African Surgical Outcomes Study - 2 (ASOS-2) here: https://www.asos.org.za/index.php/about-the-study

Presented by Desiree Chappell with Monty Mythen and their guest Paul Myles, Director, Anaesthesiology and Perioperative Medicine, Alfred Hospital and Monash University.

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Bruce Biccard is interviewed here: https://www.topmedtalk.com/prato-2019-bruce-biccard/