Over 50 % of adults and children in some Western countries have chronic diseases. Prominent among these diseases are heart disease and cognitve decline. Dr. Goodenowe discuses measurment of health status and steps towards optimal health. Progress can be measured and the risks for chronic diseases can be reduced. Plamalogens are a class of membrane glycerophospholipis and are a potential therapeutic target for neruodegenerative and cardiometabolic diseases. He will discuss this. Further information can be found at https://pubmed.ncbi.nlm.nih.gov/30974122/