Just like all the water in the ocean can't sink a ship unless the water gets inside the boat, all the negativity and toxicity in the world won't bring you down unless you let it in. Mindfulness doesn't make other people less irritating, it makes us less irritable. So, if you are still irritable, then you still have work to do. Part of that work involves no longer waiting for the world to accommodate your preferences or reacting when things don't go your way.