Psoriasis Uncovered

Psoriasis in high impact sites like the scalp, nails, genitals, palms, and soles is challenging. Hear views on living with such difficult to treat areas, and how appropriate treatments offer patient centered care from internationally recognized dermatologist Dr. Andrew Blauvelt, chair of the NPF Medical Board, patient advocates Brittany Murray and Crystal Gatlin, with moderator Corinne Rutkowski. This episode is provided with support from AbbVie.

Explore groundbreaking updates in psoriasis and psoriatic arthritis research from the 2025 AAD Annual Meeting with dermatologist Dr. Mona Shahriari.

Join host Archie Franklin and renowned dermatologist Dr. Mona Shahriari as they unpack the latest research and clinical insights into managing psoriatic disease. This episode dives into head-to-head therapeutic trials, fast-acting treatments for high-impact areas like scalp and nails, and a preview of emerging oral biologics and GLP-1 weight management therapies. Dr. Shahriari discusses real-world challenges in treating psoriasis and psoriatic arthritis, the rise of precision medicine, and how early intervention could alter disease progression.

Whether you're a patient, clinician, or researcher, this conversation delivers critical updates on psoriasis care, including IL-17, IL-23, and TYK2 inhibitors, and their potential to revolutionize dermatology practice.

• (00:00) Intro to Psound Bytes & guest welcome Dr. Mona Shahriari

• (01:00) What the AAD 2025 conference revealed about psoriatic disease

• (02:10) Comparing IL-17 and IL-23 inhibitors: Trial results

• (06:00) Treating scalp, palmoplantar, and nail psoriasis

• (10:45) Genital psoriasis & the importance of psychosocial care

• (12:00) What's new for Generalized Pustular Psoriasis (GPP)

• 14:35) The GUIDE Study: Early treatment & immune memory

• (18:00) Personalized medicine, oral IL-23s & emerging TYK2s

• (20:00) GLP-1 therapies for weight & inflammation control

• (23:00) Psoriasis, cardiovascular risk & comorbidities

• (24:00) Mental health, depression & the value of systemic treatment

• (26:00) A hopeful future: matching therapy to the patient

• Head-to-head trials show IL-17s like ixekizumab outperform traditional TNF inhibitors and even some IL-23s in early, fast action.

• Precision therapy based on site (scalp, nails, genitalia) and comorbidities is now guiding real-world treatment selection.

• GLP-1 medications are emerging as effective adjuncts for psoriasis patients struggling with weight and inflammation.

• Early intervention—especially with IL-23 inhibitors—may reduce flares, limit disease progression, and improve mental health outcomes.

Dr. Mona Shahriari is an Associate Clinical Professor of Dermatology at Yale University and Co-Founder of Central Connecticut Dermatology. A leading voice in inflammatory skin conditions, she serves as Associate Director of Clinical Trials and Senior Editor for the Journal of Psoriasis and Psoriatic Arthritis, a National Psoriasis Foundation peer reviewed journal for health care providers. Dr. Shahriari is also a National Psoriasis Foundation Medical Board Member and frequent contributor to dermatological research and clinical education.

• National Psoriasis Foundation: https://www.psoriasis.org

• Subscribe to the Advance eNewsletter: https://www.psoriasis.org/subscribe

• AAD Annual Meeting Info: https://www.aad.org

• Learn More About Clinical Trials: https://clinicaltrials.gov

psoriasis, psoriatic arthritis, IL-17, IL-23, biologics, personalized medicine, dermatology, GLP-1, weight management, immune memory, AAD 2025, TYK2 inhibitors, Dr. Mona Shahriari, National Psoriasis Foundation, Psound Bytes podcast, Soundbites podcast

Facing challenges presented by psoriasis can be an emotional roller coaster. From diagnosis, treatment choices, and the impact of bullying when a child has psoriasis can leave a parent feeling alone and helpless. Finding someone who's been on the same journey can be a benefit. Hear how parents Jessie Houston, Nadya Helt, and Emma Rhodes with moderator Michel Tarabocchia found the help and hope they needed through the NPF One to One Program.

Making an impact as a volunteer can happen in many different ways. Hear what it means to volunteer and come together to attend the NPF IMPACT Volunteer Leadership Summit as 3 fabulous volunteers, John Romano, Alena Chapman, and NPF Board Member Chris Lindsay, share their experiences and how they fundraise to make a difference in the psoriatic disease community with Carol Osterhaus, NPF Senior Regional Development Manager for the Central Region.

Having psoriasis may mean you're at risk for other diseases. Listen as moderators Alan Simmons and Kaleigh Welch explore cardiovascular disease, calcium build-up, NAFLD, sleep disorders, depression, anxiety, and the big question - does risk equal certainty with Dr. John Barbieri, Assistant Professor at Harvard Medical School, an investigator of the CP3 Study, and the Smart Phone Cognitive Behavioral Therapy Study.

The journey from the first sign of plaque psoriasis to diagnosis and beyond is very familiar to Brandon, Christy and Daryl. Hear these real patients share the good and the bad of their plaque psoriasis journeys with moderator Max Blitstein. Listen as they discuss how they became empowered self advocates by speaking up for themselves with their healthcare provider. What differences did it make for them? Tune in to find out. This episode is sponsored by Arcutis Biotherapeutics, Inc. Please see Important Safety Information and full Prescribing Information for the product mentioned in this podcast.

Inverse psoriasis is more challenging to treat and to keep under control. Learn more as we uncover inverse psoriasis from what it is, typical symptoms and sites, other potential diseases, to being a risk factor for psoriatic arthritis, and what treatments are used either alone or in combination with dermatologist Dr. Jeffrey Cohen, Director, Psoriasis Treatment Program at Yale University School of Medicine and moderator Kaitlin Walden, RN.

Listen as Jeff Brown, LB Herbert, and Kaitlin Walden share their insights on partnering with doctors, advocating for your health, and navigating relationships - whether it's dating, family, or work. They also explore the challenges of living with a visible skin disease like psoriasis and the hidden struggles of psoriatic arthritis. As LB Herbert wisely puts it "We've all got baggage. It just might be a different type of luggage".

Listen to this unique episode that is so good it had to be split into two episodes! Hear our moderators Jeff Brown, LB Herbert, and Kaitlin Walden comment honestly on what it means to live with psoriasis and psoriatic arthritis from the challenge of not knowing what each day brings, feeling confident, coping with fears, medication changes, to advocating for your own health care. It's possible you may feel the same way and learn a few tips too.

Hear this inspiring conversation about living with psoriasis as a child, being diagnosed with PsA later, and treating with a biologic from teen Sophia and college student Jackie with moderator Kaleigh Welch. Listen to their treatment journey, overcoming fears of using a biologic, and what tips they use to live each day not defined by their psoriatic disease. This episode is provided with support from Bristol Myers Squibb.