Manesh Girn is a psychedelic researcher and neuroscientist with a PhD, exploring the intersection between brain science and altered states of consciousness. In this episode, Adam and Manesh dive into how psychedelics interact with the brain, reshaping patterns of thought, perception, and identity. They unpack the latest research on how these substances are being used to treat depression and other mental health challenges, helping individuals break free from rigid mental loops and reconnect with a deeper sense of clarity and meaning.

The conversation expands beyond therapy into the potential benefits for psychologically healthy individuals, from enhanced creativity to greater emotional openness and perspective. They also explore a provocative question — if world leaders had access to these kinds of perspective-shifting experiences, could it influence global decision-making and even reduce conflict? This episode offers a forward-thinking look at the role psychedelics may play in the future of mental health, consciousness, and society as a whole.

Manesh Girn | @thepsychedelicscientist

Adam Jackson | @adam___jackson

Attend the Sacred Sons Summit 2026

Sacred Sons SUMMIT 

APRIL 11-12, 2026

San Diego, CA