In June 2008, McCants began dating reality television star Khloe Kardashian. The two were introduced by the National Football League player Reggie Bush who had been dating her sister Kim at the time. The relationship ended after seven months, in late January 2009, reportedly due to McCants's infidelity. He also made a brief guest appearance on her reality show, Keeping Up with the Kardashians, during season 3 (episode 7). Eight years later, speaking with a Charlotte Observer reporter while looking back on his career in the NBA, McCants stated that the highly publicized relationship with Khloe Kardashian was the "biggest regret" because it "gave people an opportunity to doubt his commitment to the NBA", adding: "Without that situation in play, I’m a $60-70 million player. Easily."

McCants was one of the victims of professional scam artist/fraudster Peggy Ann Fulford losing $200,000, amongst the $5.79 million in total she stole from him, Ricky Williams, Travis Best, Dennis Rodman, Lex Hilliard and others. Fulford, who was indicted by the FBI in December 2016, continued her criminal activity until sentenced in February 2018 to 10 years in prison and full financial restitution to her victims.

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