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The latest podcast by Sue Yom, MD, Editor-in-Chief of the International Journal of Radiation Oncology, Biology, Physics addresses the status of hypofractionation in radiation therapy for locoregonally advanced lung cancer. Articles discussed include Hoppe et al.’s article "Chemoradiation with Hypofractionated Proton Therapy in Stage II-III Non-Small Cell Lung Cancer: A Proton Collaborative Group Phase 2 Trial", Contreras et al.’s article "Phase I Study of Accelerated Hypofractionated Proton Therapy and Chemotherapy for Locally Advanced Non Small Cell Lung Cancer", and Brownstein and Salama’s editorial, "Moderately Hypofractionated Proton Beam Therapy for Locally Advanced Non-Small Cell Lung Cancer: A New Way Forward for Dose Escalation?" which is available in the July 15, 2022 issue.