Our Editor-in-Chief Dr. Sue Yom co-hosts with Dr. Henning Willers, our journal's Biology Section Editor and Associate Professor of Radiation Oncology at Massachusetts General Hospital. Guests are Dr. Simon Powell, Chair of Memorial Sloan Kettering Cancer Center Department of Radiation Oncology, who joins us as the co-last author of a new publication, Increased synthetic cytotoxicity of combinatorial chemoradiotherapy in homologous recombination deficient tumors, and Dr. Kerstin Borkmann, Professor of Radiobiology at the University Clinic Hamburg Eppendorf and Biology Associate Editor for our journal. She is the co-author of the accompanying editorial, BRCAness identifies synthetic cytotoxicity between cisplatin and RT.