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Can a nerve regenerate without surgery? This case suggests yes.

In this episode of Pod of Inquiry, Dr. Stephen Barrett sits down with Dr. Erin Nelson to review a rare EMG-documented case of nerve regeneration after ultrasound-guided Hydrodissection with D5W — no scalpel required.

A 56-year-old woman developed sudden foot drop due to deep peroneal nerve entrapment. After two D5W Hydrodissection sessions, a 4-month repeat EMG showed significant interval improvement in demyelination + axonal injury. Objective. Measurable. Independent neurologist confirmed.

🎯 What you'll learn in this episode: • Why 5% dextrose (D5W) outperforms saline in Hydrodissection • The exact protocol Dr. Nelson uses (volume, frequency, technique) • When to choose Hydrodissection vs. surgical decompression • Implications for patients with diabetic neuropathy • The difference between glucose puncture vs Hydrodissection

This may become one of the most important clinical conversations in the nerve pain / peripheral neuropathy space.

Visit our website https://podofinquiry.com/latest-episodes/ - click on the show link to read the show notes and get more information.

Timestamps: 00:00 - Introduction 00:52 - Opening & Welcome 02:39 - What is Hydrodissection? 04:03 - Why D5W Over Other Solutions? 05:33 - Safety in Diabetic Patients 07:12 - Safety Profile & Substance P 07:50 - Glucose Puncture vs Hydrodissection 09:48 - Case Presentation Begins 10:00 - Patient History 13:47 - Prior Upper Extremity Surgeries 17:09 - EMG Findings 18:17 - Weight Loss Connection 19:24 - Physical Examination 22:59 - First Hydrodissection 23:03 - One Month Follow-up 23:16 - Second Hydrodissection 25:45 - EMG Improvement 26:33 - Significance of Objective Findings 27:06 - Current Status 30:19 - Causes of Nerve Entrapment 31:48 - Hydrodissection Mechanism Review 33:20 - Patient Experience 34:41 - Future Considerations 36:39 - Conservative Approach Benefits 39:39 - Residual Symptoms & Central Sensitization 41:04 - Complexity of Treatment 42:17 - Contact Information

-- Hashtags -- #D5WHydrodissection #NerveRegeneration #Electrodiagnostics #EMG #Neuropathy #PeripheralNerve #UltrasoundGuidedProcedures #PainMedicine #RegenerativeMedicine