In this episode, hosts David Anderson and Gina Vitale travel as far back as ancient Egypt to unearth the wide-ranging uses of retinol. They also bring in C&EN reporter Craig Bettenhausen to discuss why retinol is such a powerhouse molecule for skin care, and they hear from a contraceptives researcher about how an early candidate for a birth control pill for men affected the retinol pathway.

C&EN's award-winning podcast Inflection Point leans on our 100-year archive to trace headline topics in science today back to their disparate and surprising roots. In each episode, we explore three lesser-known moments in science history that ultimately led us to current-day breakthroughs. With help from expert C&EN reporters, this show examines how discoveries from our past have shaped our present and will change our future.

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Correction:

This episode was updated on June 10, 2026 to correct an error in the name of a new birth control candidate for men. It is YCT-529, not YTC-529.